Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1447868..1448507 Replicon chromosome
Accession NZ_CP030057
Organism Bradyrhizobium guangdongense strain CCBAU 51658

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag XH86_RS06810 Protein ID WP_128964133.1
Coordinates 1448214..1448507 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag XH86_RS06805 Protein ID WP_128964132.1
Coordinates 1447868..1448209 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH86_RS06780 1443822..1444073 - 252 WP_128964127.1 hypothetical protein -
XH86_RS06785 1444094..1444540 - 447 WP_128964128.1 GNAT family N-acetyltransferase -
XH86_RS06790 1444540..1445568 - 1029 WP_128964129.1 peptidoglycan -binding protein -
XH86_RS06795 1445593..1446612 - 1020 WP_164938453.1 flagellar motor protein MotA -
XH86_RS06800 1446834..1447871 + 1038 WP_128964131.1 cyclopropane-fatty-acyl-phospholipid synthase family protein -
XH86_RS06805 1447868..1448209 - 342 WP_128964132.1 putative addiction module antidote protein Antitoxin
XH86_RS06810 1448214..1448507 - 294 WP_128964133.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XH86_RS06815 1448876..1450069 + 1194 WP_128964134.1 efflux RND transporter periplasmic adaptor subunit -
XH86_RS06820 1450076..1453228 + 3153 WP_128964135.1 multidrug efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10613.26 Da        Isoelectric Point: 10.0403

>T106963 WP_128964133.1 NZ_CP030057:c1448507-1448214 [Bradyrhizobium guangdongense]
VVDVVQTEAFRSWLAGLHDRRAVARIASRIALIERGALGDVKSLGAGLSEFRIDYGPGYRLYAAQRGAVTVILLCGGDKR
KQSADIKRARAMLEELE

Download         Length: 294 bp

>T106963 NZ_CP030057:c1448507-1448214 [Bradyrhizobium guangdongense]
GTGGTCGATGTTGTACAGACAGAAGCATTTCGGAGCTGGCTTGCCGGATTACACGACCGTCGCGCAGTTGCGCGCATCGC
AAGCCGAATCGCATTGATCGAACGCGGCGCACTTGGCGACGTGAAGTCTTTGGGAGCGGGCCTGTCTGAATTCAGAATTG
ACTACGGCCCGGGCTATCGACTCTATGCGGCACAACGTGGAGCCGTGACGGTCATCCTGCTCTGCGGTGGCGACAAGCGA
AAGCAATCTGCGGACATCAAGCGGGCACGGGCCATGCTTGAGGAACTGGAGTAG

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 11954.70 Da        Isoelectric Point: 10.4635

>AT106963 WP_128964132.1 NZ_CP030057:c1448209-1447868 [Bradyrhizobium guangdongense]
MALKTTPFDAAEYLDTPEAQAEFITAALETGDAAFIRDSVNTVARARGMSEIAKSTGLSREGLYKALGETGNPEFSTMLG
VLRALGLGLTARPLSRKPSKPRKTAKPRASKAA

Download         Length: 342 bp

>AT106963 NZ_CP030057:c1448209-1447868 [Bradyrhizobium guangdongense]
ATGGCGCTGAAAACAACACCATTTGATGCGGCGGAATATTTGGATACGCCGGAAGCACAAGCCGAATTCATTACGGCTGC
GCTGGAGACAGGCGACGCGGCATTCATTCGTGACTCCGTGAATACCGTTGCGCGTGCCCGCGGCATGAGCGAGATAGCAA
AATCGACGGGGCTGAGCCGCGAGGGGTTGTACAAGGCCCTCGGCGAGACCGGAAATCCGGAGTTCTCGACAATGCTGGGG
GTATTGCGCGCGCTTGGCTTAGGTCTGACTGCGCGCCCCTTATCCAGGAAGCCAAGTAAGCCGCGCAAAACAGCAAAGCC
GCGAGCCAGCAAGGCTGCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References