Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB-HicA
Location 549561..550153 Replicon plasmid unnamed1
Accession NZ_CP030054
Organism Bradyrhizobium guangzhouense strain CCBAU 51670

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag XH91_RS36575 Protein ID WP_128929956.1
Coordinates 549965..550153 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag XH91_RS36570 Protein ID WP_128929955.1
Coordinates 549561..549959 (-) Length 133 a.a.

Genomic Context

XH91_RS36550XH91_RS36565XH91_RS36605XH91_RS36555XH91_RS36560XH91_RS36570XH91_RS36575XH91_RS36580XH91_RS36585XH91_RS36590XH91_RS36595XH91_RS36600
Location: 544840..545160 (321 bp)
Type: Others
Protein ID: WP_128929952.1
Location: 547711..548907 (1197 bp)
Type: Others
Protein ID: Protein_492
Location: 553906..554235 (330 bp)
Type: Others
Protein ID: WP_128930197.1
Location: 545439..546662 (1224 bp)
Type: Others
Protein ID: WP_128929953.1
Location: 546655..547233 (579 bp)
Type: Others
Protein ID: WP_128929954.1
Location: 549561..549959 (399 bp)
Type: Antitoxin
Protein ID: WP_128929955.1
Location: 549965..550153 (189 bp)
Type: Toxin
Protein ID: WP_128929956.1
Location: 550229..550819 (591 bp)
Type: Others
Protein ID: WP_128930143.1
Location: 550852..552411 (1560 bp)
Type: Others
Protein ID: WP_128929539.1
Location: 552462..552816 (355 bp)
Type: Others
Protein ID: Protein_497
Location: 552813..553286 (474 bp)
Type: Others
Protein ID: WP_128929538.1
Location: 553463..553837 (375 bp)
Type: Others
Protein ID: WP_188637391.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XH91_RS36550544840..545160+321WP_128929952.1ferredoxin family protein-
XH91_RS36555545439..546662-1224WP_128929953.1type II toxin-antitoxin system HipA family toxin-
XH91_RS36560546655..547233-579WP_128929954.1helix-turn-helix domain-containing protein-
XH91_RS36565547711..548907+1197Protein_492Fic family protein-
XH91_RS36570549561..549959-399WP_128929955.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
XH91_RS36575549965..550153-189WP_128929956.1type II toxin-antitoxin system HicA family toxinToxin
XH91_RS36580550229..550819-591WP_128930143.1UPF0149 family protein-
XH91_RS36585550852..552411-1560WP_128929539.1IS66 family transposase-
XH91_RS36590552462..552816-355Protein_497IS66 family insertion sequence element accessory protein TnpB-
XH91_RS36595552813..553286-474WP_128929538.1transposase-
XH91_RS36600553463..553837-375WP_188637391.1hypothetical protein-
XH91_RS36605553906..554235+330WP_128930197.1EAL domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-gmd1..979291979291


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-124)


Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7077.32 Da        Isoelectric Point: 11.2092

>T106961 WP_128929956.1 NZ_CP030054:c550153-549965 [Bradyrhizobium guangzhouense]
MKSREIISILQGDGWFEVGRKGSHVQFKHPFKKGRVIVPHPERDVPLGTLKSIEKQSGLKLR

Download         Length: 189 bp

>T106961 NZ_CP030054:c550153-549965 [Bradyrhizobium guangzhouense]
ATGAAAAGCCGGGAAATTATCTCGATCCTTCAAGGGGATGGATGGTTTGAGGTGGGCCGGAAAGGCAGCCATGTGCAGTT
CAAACATCCATTCAAGAAGGGTCGCGTAATTGTTCCGCACCCCGAACGGGATGTCCCACTCGGGACACTGAAGAGTATTG
AAAAGCAGTCAGGTCTCAAACTGAGGTAA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14163.96 Da        Isoelectric Point: 4.3695

>AT106961 WP_128929955.1 NZ_CP030054:c549959-549561 [Bradyrhizobium guangzhouense]
MRNYIGLIHKDADSDFGVSFPDFPGVITAGKSLDDARAMAEEALTLHIEGLAEDGEAIPEPSTLEDVMADPDHRTGVAIL
VSVKPEQPKAIRVNVTLPEDVLNQIDKYAEAHGFTRSGLLTQAAKRLIGEAA

Download         Length: 399 bp

>AT106961 NZ_CP030054:c549959-549561 [Bradyrhizobium guangzhouense]
ATGCGTAACTATATTGGTCTTATCCATAAGGATGCCGACAGCGATTTCGGCGTCTCATTTCCAGACTTCCCCGGAGTGAT
CACGGCAGGCAAAAGCCTTGATGACGCTCGTGCTATGGCAGAGGAAGCCCTCACCCTTCATATCGAGGGTCTTGCTGAAG
ATGGAGAAGCCATTCCGGAGCCCTCTACTCTAGAGGATGTTATGGCAGATCCTGATCATCGAACTGGGGTAGCTATTTTG
GTGTCGGTCAAACCCGAACAACCAAAGGCTATACGTGTGAATGTCACCCTTCCTGAGGACGTTCTGAATCAGATCGACAA
ATATGCTGAAGCGCACGGCTTTACGAGATCGGGCCTCCTAACTCAGGCCGCGAAGAGACTCATAGGAGAAGCAGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References