Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5731100..5731773 Replicon chromosome
Accession NZ_CP030053
Organism Bradyrhizobium guangzhouense strain CCBAU 51670

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag XH91_RS27415 Protein ID WP_128953482.1
Coordinates 5731351..5731773 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XH91_RS27410 Protein ID WP_128953481.1
Coordinates 5731100..5731354 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH91_RS27380 5726512..5727114 + 603 WP_128953475.1 ParB/Srx family N-terminal domain-containing protein -
XH91_RS27385 5727855..5728394 + 540 WP_128953476.1 hypothetical protein -
XH91_RS27390 5728679..5729095 - 417 WP_128953477.1 hypothetical protein -
XH91_RS27395 5729395..5730093 - 699 WP_128953478.1 hypothetical protein -
XH91_RS27400 5730311..5730706 - 396 WP_128953479.1 type II toxin-antitoxin system VapC family toxin -
XH91_RS27405 5730703..5730957 - 255 WP_128953480.1 type II toxin-antitoxin system VapB family antitoxin -
XH91_RS27410 5731100..5731354 + 255 WP_128953481.1 plasmid stabilization protein Antitoxin
XH91_RS27415 5731351..5731773 + 423 WP_128953482.1 type II toxin-antitoxin system VapC family toxin Toxin
XH91_RS27420 5731934..5733244 - 1311 WP_128953483.1 ParB N-terminal domain-containing protein -
XH91_RS27425 5733348..5733863 - 516 WP_128953484.1 hypothetical protein -
XH91_RS27430 5733872..5734522 - 651 WP_128953485.1 hypothetical protein -
XH91_RS27435 5734968..5735483 - 516 WP_128953486.1 hypothetical protein -
XH91_RS27440 5735665..5735910 + 246 WP_128953487.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14792.09 Da        Isoelectric Point: 8.5895

>T106960 WP_128953482.1 NZ_CP030053:5731351-5731773 [Bradyrhizobium guangzhouense]
MILLDTNVVSEAMKPEPHPSVRGWLDAQAAETVFLSSVTIAELLFGIGALPRGKRRERLATALDGVLDLFAARILPFDTT
AARRYADLVVKGRAAGKGFPTPDGYIAAIAAAHGFVVASRDTSAFKAAGLTIIDPWTVAS

Download         Length: 423 bp

>T106960 NZ_CP030053:5731351-5731773 [Bradyrhizobium guangzhouense]
ATGATCTTGCTCGATACCAATGTTGTCTCCGAGGCGATGAAGCCCGAACCCCATCCGTCGGTCCGTGGCTGGCTCGACGC
CCAGGCCGCCGAGACGGTGTTTCTCTCCAGCGTTACGATCGCCGAGCTGTTGTTCGGCATCGGCGCACTGCCACGCGGCA
AGCGCAGGGAGCGGCTGGCGACTGCGCTCGACGGCGTGCTGGACCTGTTCGCGGCCCGCATTCTGCCCTTCGATACCACC
GCGGCGCGGCGATACGCCGATCTCGTTGTCAAGGGGCGCGCGGCCGGAAAAGGCTTCCCCACGCCCGACGGCTATATTGC
CGCGATCGCCGCCGCGCACGGGTTCGTGGTGGCATCGCGGGACACGAGCGCGTTCAAGGCCGCCGGTCTGACGATCATCG
ATCCCTGGACCGTGGCCAGCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9359.66 Da        Isoelectric Point: 9.0476

>AT106960 WP_128953481.1 NZ_CP030053:5731100-5731354 [Bradyrhizobium guangzhouense]
MAAVTIRHLSEETHRALKVRAAQHNRSTEAEMRAILEAAVRPEGRLRLGTALSEMSRKIGLTNADVEALEHGRDARAAEP
MRFE

Download         Length: 255 bp

>AT106960 NZ_CP030053:5731100-5731354 [Bradyrhizobium guangzhouense]
ATGGCCGCTGTCACCATCCGCCACCTCTCCGAGGAGACGCATCGCGCCCTCAAAGTCCGCGCCGCGCAGCACAATCGCAG
CACGGAGGCCGAAATGCGCGCCATTCTGGAGGCCGCCGTACGACCCGAGGGCCGGCTGCGGCTCGGCACCGCCCTTTCGG
AAATGAGCCGGAAGATCGGCCTCACCAATGCCGACGTCGAGGCACTCGAGCATGGCCGCGACGCGCGTGCCGCTGAGCCG
ATGCGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References