Detailed information of TA system TA106959

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 5730311..5730957
• Replicon: chromosome
• Accession: NZ_CP030053
• Organism: Bradyrhizobium guangzhouense strain CCBAU 51670

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: XH91_RS27400
• Protein ID: WP_128953479.1
• Coordinates: 5730311..5730706 (-)
• Length: 132 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: XH91_RS27405
• Protein ID: WP_128953480.1
• Coordinates: 5730703..5730957 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XH91_RS27365	5725392..5725568	-	177	Protein_5375	VapC toxin family PIN domain ribonuclease	-
XH91_RS27370	5725565..5725810	-	246	WP_128953473.1	plasmid stabilization protein	-
XH91_RS27375	5726016..5726306	+	291	WP_128953474.1	hypothetical protein	-
XH91_RS27380	5726512..5727114	+	603	WP_128953475.1	ParB/Srx family N-terminal domain-containing protein	-
XH91_RS27385	5727855..5728394	+	540	WP_128953476.1	hypothetical protein	-
XH91_RS27390	5728679..5729095	-	417	WP_128953477.1	hypothetical protein	-
XH91_RS27395	5729395..5730093	-	699	WP_128953478.1	hypothetical protein	-
XH91_RS27400	5730311..5730706	-	396	WP_128953479.1	type II toxin-antitoxin system VapC family toxin	Toxin
XH91_RS27405	5730703..5730957	-	255	WP_128953480.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
XH91_RS27410	5731100..5731354	+	255	WP_128953481.1	plasmid stabilization protein	-
XH91_RS27415	5731351..5731773	+	423	WP_128953482.1	type II toxin-antitoxin system VapC family toxin	-
XH91_RS27420	5731934..5733244	-	1311	WP_128953483.1	ParB N-terminal domain-containing protein	-
XH91_RS27425	5733348..5733863	-	516	WP_128953484.1	hypothetical protein	-
XH91_RS27430	5733872..5734522	-	651	WP_128953485.1	hypothetical protein	-
XH91_RS27435	5734968..5735483	-	516	WP_128953486.1	hypothetical protein	-
XH91_RS27440	5735665..5735910	+	246	WP_128953487.1	helix-turn-helix transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	5715527..5730957	15430

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-125)

Antitoxin

• Antitoxin VapB-like (1-83)

Sequences

Toxin

Protein

• Length: 132 a.a.
• Molecular weight: 14231.13 Da
• Isoelectric Point: 5.1881

>T106959 WP_128953479.1 NZ_CP030053:c5730706-5730311 [Bradyrhizobium guangzhouense]
MIVDTSALIAILRNEPEAQRCALAIESHPIRRISAANFVEAAVVIDASRDPIASRRFDELMKEAQISIESVTQAQAQVAR
EAYRDFGKGSGHPARLNFGDCFAYALAKSTGEPLLFKGDDFIHTDIVSAAP

Nucleotide

• Length: 396 bp

>T106959 NZ_CP030053:c5730706-5730311 [Bradyrhizobium guangzhouense]
ATGATCGTCGATACATCTGCGCTCATTGCCATCCTGCGCAATGAGCCCGAGGCACAGCGCTGCGCACTTGCAATCGAATC
TCATCCCATTCGACGGATATCCGCTGCAAATTTCGTCGAGGCCGCCGTCGTGATCGATGCCAGCCGGGATCCTATCGCCA
GCCGGCGTTTCGACGAACTGATGAAGGAAGCGCAGATTTCGATCGAATCTGTGACTCAGGCTCAGGCGCAAGTCGCACGC
GAAGCCTATCGCGATTTCGGCAAGGGCAGCGGCCATCCTGCCAGACTGAATTTTGGCGACTGCTTTGCTTACGCGCTCGC
CAAAAGTACTGGCGAGCCTTTGTTGTTCAAGGGTGACGATTTCATCCATACCGATATCGTTTCGGCCGCCCCGTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9477.75 Da
• Isoelectric Point: 9.7570

>AT106959 WP_128953480.1 NZ_CP030053:c5730957-5730703 [Bradyrhizobium guangzhouense]
MSLNIKNPEAHELATELAQRTGESLTAAVTNALRERLERVRRKQGARLSDRLLKIGGDCAKHLKEPYRSADHGDLLYDER
GLPR

Nucleotide

• Length: 255 bp

>AT106959 NZ_CP030053:c5730957-5730703 [Bradyrhizobium guangzhouense]
ATGAGTTTGAACATCAAGAATCCCGAAGCCCATGAACTAGCGACAGAACTAGCACAGCGGACCGGGGAGTCGCTGACTGC
GGCGGTGACGAATGCCCTTCGTGAGCGGCTCGAGCGGGTTCGCCGCAAGCAAGGCGCACGTCTATCGGATCGTTTGCTGA
AGATCGGTGGGGATTGCGCTAAGCACTTGAAAGAGCCGTACCGATCGGCCGATCACGGCGATCTGCTCTACGACGAGCGC
GGATTGCCTCGATGA