Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1315488..1316127 Replicon chromosome
Accession NZ_CP030053
Organism Bradyrhizobium guangzhouense strain CCBAU 51670

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag XH91_RS06435 Protein ID WP_128949796.1
Coordinates 1315834..1316127 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag XH91_RS06430 Protein ID WP_128949795.1
Coordinates 1315488..1315829 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH91_RS06400 1310813..1311259 - 447 WP_128949790.1 GNAT family N-acetyltransferase -
XH91_RS06405 1311259..1312287 - 1029 WP_128949791.1 peptidoglycan -binding protein -
XH91_RS06410 1312440..1313465 - 1026 WP_164933615.1 flagellar motor protein MotA -
XH91_RS06420 1313648..1314457 + 810 WP_128949793.1 DUF1295 domain-containing protein -
XH91_RS06425 1314454..1315485 + 1032 WP_128949794.1 cyclopropane-fatty-acyl-phospholipid synthase family protein -
XH91_RS06430 1315488..1315829 - 342 WP_128949795.1 putative addiction module antidote protein Antitoxin
XH91_RS06435 1315834..1316127 - 294 WP_128949796.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XH91_RS06440 1316422..1317615 + 1194 WP_128949797.1 efflux RND transporter periplasmic adaptor subunit -
XH91_RS06445 1317863..1321015 + 3153 WP_128949798.1 multidrug efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(3-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10602.28 Da        Isoelectric Point: 10.7019

>T106957 WP_128949796.1 NZ_CP030053:c1316127-1315834 [Bradyrhizobium guangzhouense]
VTDVVQTDAFRNWLAGLRDRRAVARIASRIALIERGALGDVKSLGGGLSEFKIDYGPGYRLFAAQRGTVTVILLCGGDKR
KQQADIKRARAMLAELE

Download         Length: 294 bp

>T106957 NZ_CP030053:c1316127-1315834 [Bradyrhizobium guangzhouense]
GTGACCGATGTCGTGCAGACGGATGCATTTCGAAACTGGCTTGCCGGGTTGCGCGACCGTCGCGCAGTGGCGCGCATCGC
AAGCCGAATCGCATTGATCGAACGCGGCGCGCTTGGCGATGTGAAGTCCTTGGGCGGGGGGCTGTCTGAATTCAAGATAG
ACTACGGCCCGGGGTATCGTCTTTTTGCCGCGCAACGCGGAACCGTGACGGTCATTCTGCTCTGTGGTGGCGACAAGCGA
AAGCAACAAGCCGACATCAAGCGGGCACGGGCGATGCTTGCAGAACTGGAGTAA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 11982.76 Da        Isoelectric Point: 10.5812

>AT106957 WP_128949795.1 NZ_CP030053:c1315829-1315488 [Bradyrhizobium guangzhouense]
MALKTTPFDAAEYLDTPEAQAEFITAALETGDAAFIRDSVNTVARARGMSEIAKSTGLSREGLYKALGEAGNPEFSTMLG
VLRALGLGLTARPLPKKSGKQRKSAKPRTRKAA

Download         Length: 342 bp

>AT106957 NZ_CP030053:c1315829-1315488 [Bradyrhizobium guangzhouense]
ATGGCGCTGAAAACAACACCATTTGACGCGGCGGAATATCTGGATACGCCGGAAGCACAGGCCGAATTCATCACAGCAGC
GCTGGAGACTGGCGACGCGGCGTTCATCCGTGATTCCGTGAATACGGTTGCGCGAGCCCGCGGCATGAGCGAGATAGCAA
AATCGACAGGGCTGAGCCGCGAAGGGCTGTACAAGGCACTCGGCGAGGCCGGAAATCCGGAGTTCTCAACAATGTTGGGG
GTATTGCGCGCGCTTGGCTTGGGTCTGACTGCGCGTCCCTTGCCCAAAAAGTCCGGCAAGCAGCGCAAGTCAGCGAAGCC
GCGAACCCGCAAGGCTGCCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References