Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 463926..464584 Replicon chromosome
Accession NZ_CP030053
Organism Bradyrhizobium guangzhouense strain CCBAU 51670

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag XH91_RS02305 Protein ID WP_128949090.1
Coordinates 463926..464330 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XH91_RS02310 Protein ID WP_128949091.1
Coordinates 464330..464584 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH91_RS02285 459216..461786 - 2571 WP_128949087.1 FtsX-like permease family protein -
XH91_RS02290 461783..462505 - 723 WP_128949088.1 ABC transporter ATP-binding protein -
XH91_RS02295 462561..463196 + 636 WP_164934305.1 arylesterase -
XH91_RS02300 463371..463907 + 537 WP_128949089.1 RNA 2',3'-cyclic phosphodiesterase -
XH91_RS02305 463926..464330 - 405 WP_128949090.1 type II toxin-antitoxin system VapC family toxin Toxin
XH91_RS02310 464330..464584 - 255 WP_128949091.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
XH91_RS02315 464780..465967 + 1188 WP_128949092.1 cell division protein ZapE -
XH91_RS02320 466230..467198 + 969 WP_128949093.1 malate dehydrogenase -
XH91_RS02325 467413..468609 + 1197 WP_128949094.1 ADP-forming succinate--CoA ligase subunit beta -
XH91_RS02330 468614..469093 + 480 WP_128949095.1 DUF1579 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14532.52 Da        Isoelectric Point: 4.9362

>T106955 WP_128949090.1 NZ_CP030053:c464330-463926 [Bradyrhizobium guangzhouense]
MVIDTSAIVAIAFNEDDAADMERLIVDDPVRLISAATVLEATMVIETRLGDAGGREFDLWLVKVGAEIVAVDAGQADAAR
RAWRRYGKGRHVASLNYGDCFSYALAVTRSEPLLFKGADFAKTDVSRSSVAPRR

Download         Length: 405 bp

>T106955 NZ_CP030053:c464330-463926 [Bradyrhizobium guangzhouense]
ATGGTAATCGATACGTCGGCGATCGTGGCAATCGCGTTCAACGAAGACGATGCAGCGGATATGGAGCGACTGATCGTGGA
CGATCCGGTCCGCCTGATCTCTGCAGCAACGGTGCTTGAAGCAACGATGGTGATCGAGACTCGGCTAGGTGATGCGGGCG
GGCGCGAGTTCGATCTGTGGCTCGTCAAGGTCGGCGCCGAGATCGTGGCAGTCGATGCCGGCCAGGCCGATGCAGCACGG
CGAGCTTGGCGGCGCTACGGGAAAGGGCGACATGTTGCATCGCTCAACTATGGGGATTGCTTCTCTTACGCGCTGGCTGT
GACGCGCAGCGAACCGCTGCTGTTCAAAGGCGCGGACTTTGCGAAGACCGACGTCAGCCGATCGAGCGTGGCGCCACGGC
GCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9623.86 Da        Isoelectric Point: 5.1974

>AT106955 WP_128949091.1 NZ_CP030053:c464584-464330 [Bradyrhizobium guangzhouense]
MALSIKDPETEQLARSLAQLTGENITTATKRAIEERLRRLGGQTHKDALLQDMAEIRKRWSEMRVLDDRTSEEIVGYDEN
GLPR

Download         Length: 255 bp

>AT106955 NZ_CP030053:c464584-464330 [Bradyrhizobium guangzhouense]
ATGGCGCTTAGCATCAAGGACCCTGAAACGGAGCAGTTGGCGCGGAGTCTGGCGCAATTGACCGGCGAGAACATCACGAC
AGCGACCAAGCGGGCCATCGAGGAGCGGTTGCGTCGGCTCGGCGGTCAAACTCACAAAGACGCGCTGCTTCAAGACATGG
CCGAAATCAGGAAGCGCTGGAGCGAAATGCGCGTCCTGGATGACCGCACGTCTGAGGAGATCGTCGGATACGATGAGAAT
GGATTGCCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References