Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1449256..1449895 Replicon chromosome
Accession NZ_CP030051
Organism Bradyrhizobium guangdongense strain CCBAU 51649

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag X265_RS06935 Protein ID WP_128964133.1
Coordinates 1449602..1449895 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag X265_RS06930 Protein ID WP_128964132.1
Coordinates 1449256..1449597 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
X265_RS06905 1445210..1445461 - 252 WP_128964127.1 hypothetical protein -
X265_RS06910 1445482..1445928 - 447 WP_128964128.1 GNAT family N-acetyltransferase -
X265_RS06915 1445928..1446956 - 1029 WP_128964129.1 peptidoglycan -binding protein -
X265_RS06920 1446981..1448000 - 1020 WP_164938453.1 flagellar motor protein MotA -
X265_RS06925 1448222..1449259 + 1038 WP_128964131.1 cyclopropane-fatty-acyl-phospholipid synthase family protein -
X265_RS06930 1449256..1449597 - 342 WP_128964132.1 putative addiction module antidote protein Antitoxin
X265_RS06935 1449602..1449895 - 294 WP_128964133.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
X265_RS06940 1450264..1451457 + 1194 WP_128964134.1 efflux RND transporter periplasmic adaptor subunit -
X265_RS06945 1451464..1454616 + 3153 WP_128964135.1 multidrug efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10613.26 Da        Isoelectric Point: 10.0403

>T106953 WP_128964133.1 NZ_CP030051:c1449895-1449602 [Bradyrhizobium guangdongense]
VVDVVQTEAFRSWLAGLHDRRAVARIASRIALIERGALGDVKSLGAGLSEFRIDYGPGYRLYAAQRGAVTVILLCGGDKR
KQSADIKRARAMLEELE

Download         Length: 294 bp

>T106953 NZ_CP030051:c1449895-1449602 [Bradyrhizobium guangdongense]
GTGGTCGATGTTGTACAGACAGAAGCATTTCGGAGCTGGCTTGCCGGATTACACGACCGTCGCGCAGTTGCGCGCATCGC
AAGCCGAATCGCATTGATCGAACGCGGCGCACTTGGCGACGTGAAGTCTTTGGGAGCGGGCCTGTCTGAATTCAGAATTG
ACTACGGCCCGGGCTATCGACTCTATGCGGCACAACGTGGAGCCGTGACGGTCATCCTGCTCTGCGGTGGCGACAAGCGA
AAGCAATCTGCGGACATCAAGCGGGCACGGGCCATGCTTGAGGAACTGGAGTAG

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 11954.70 Da        Isoelectric Point: 10.4635

>AT106953 WP_128964132.1 NZ_CP030051:c1449597-1449256 [Bradyrhizobium guangdongense]
MALKTTPFDAAEYLDTPEAQAEFITAALETGDAAFIRDSVNTVARARGMSEIAKSTGLSREGLYKALGETGNPEFSTMLG
VLRALGLGLTARPLSRKPSKPRKTAKPRASKAA

Download         Length: 342 bp

>AT106953 NZ_CP030051:c1449597-1449256 [Bradyrhizobium guangdongense]
ATGGCGCTGAAAACAACACCATTTGATGCGGCGGAATATTTGGATACGCCGGAAGCACAAGCCGAATTCATTACGGCTGC
GCTGGAGACAGGCGACGCGGCATTCATTCGTGACTCCGTGAATACCGTTGCGCGTGCCCGCGGCATGAGCGAGATAGCAA
AATCGACGGGGCTGAGCCGCGAGGGGTTGTACAAGGCCCTCGGCGAGACCGGAAATCCGGAGTTCTCGACAATGCTGGGG
GTATTGCGCGCGCTTGGCTTAGGTCTGACTGCGCGCCCCTTATCCAGGAAGCCAAGTAAGCCGCGCAAAACAGCAAAGCC
GCGAGCCAGCAAGGCTGCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References