Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2568007..2568710 Replicon chromosome
Accession NZ_CP030050
Organism Bradyrhizobium arachidis strain CCBAU 051107

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag WN72_RS11820 Protein ID WP_092218130.1
Coordinates 2568007..2568429 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag WN72_RS11825 Protein ID WP_092218129.1
Coordinates 2568426..2568710 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WN72_RS11790 2564060..2564470 + 411 WP_027564302.1 acyl-CoA thioesterase -
WN72_RS11795 2564661..2564852 + 192 WP_024341426.1 hypothetical protein -
WN72_RS11800 2564996..2565388 - 393 WP_092218131.1 nuclear transport factor 2 family protein -
WN72_RS11805 2565760..2566212 - 453 WP_027564304.1 nuclear transport factor 2 family protein -
WN72_RS11810 2566367..2567053 + 687 WP_092218169.1 HAD-IA family hydrolase -
WN72_RS11815 2567157..2568002 + 846 WP_027564306.1 DeoR/GlpR family DNA-binding transcription regulator -
WN72_RS11820 2568007..2568429 - 423 WP_092218130.1 type II toxin-antitoxin system VapC family toxin Toxin
WN72_RS11825 2568426..2568710 - 285 WP_092218129.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
WN72_RS11830 2568942..2570492 + 1551 WP_027564309.1 glycerol-3-phosphate dehydrogenase -
WN72_RS11835 2570489..2571568 + 1080 WP_092218128.1 ABC transporter ATP-binding protein -
WN72_RS11840 2571580..2572665 + 1086 WP_027564311.1 ABC transporter ATP-binding protein -
WN72_RS11845 2572665..2573639 + 975 WP_027564312.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(15-77)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15433.74 Da        Isoelectric Point: 6.4735

>T106952 WP_092218130.1 NZ_CP030050:c2568429-2568007 [Bradyrhizobium arachidis]
VNLLLDANVLSEVRRPAPSPKVLAWLDTIDEDRTFISVASIAELRRGVALLEDGRRRTALAAWLTHDLPARFAERVLPID
HAVAERWGDLMAQSRRSGVVLSVMDGFFAATALANSLTLVTRNVKDFAPYGLSLLNPWDA

Download         Length: 423 bp

>T106952 NZ_CP030050:c2568429-2568007 [Bradyrhizobium arachidis]
GTGAACCTGCTGCTCGACGCGAACGTACTGTCCGAGGTTCGGCGGCCTGCGCCTTCGCCGAAAGTTCTGGCGTGGCTTGA
TACGATCGATGAGGATCGCACTTTCATCAGTGTTGCCTCGATCGCCGAGCTTCGCCGCGGCGTGGCGTTGCTGGAGGACG
GCCGTCGGCGCACAGCGTTAGCCGCCTGGCTGACTCATGATCTACCGGCGCGGTTTGCCGAACGCGTCCTGCCGATCGAC
CACGCGGTGGCGGAACGCTGGGGCGACCTGATGGCGCAGAGCCGCAGAAGTGGCGTCGTATTGTCTGTCATGGACGGCTT
CTTTGCCGCAACCGCGCTCGCGAACAGCCTCACGCTCGTCACGCGCAATGTGAAGGATTTTGCACCGTACGGCCTGTCGC
TGCTCAACCCGTGGGACGCCTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10282.64 Da        Isoelectric Point: 5.6921

>AT106952 WP_092218129.1 NZ_CP030050:c2568710-2568426 [Bradyrhizobium arachidis]
MVDSNPAPATLPTDDTWTLANAKARLSEVIDRAQTGPQVITRHGKPNAVVVSVEEWARKVARKGTLAEFLLASPLRGADL
ELDRVHDTPRDEMP

Download         Length: 285 bp

>AT106952 NZ_CP030050:c2568710-2568426 [Bradyrhizobium arachidis]
ATGGTCGACAGCAACCCTGCACCTGCCACGCTTCCGACTGATGACACTTGGACGCTCGCCAATGCCAAGGCACGGCTGTC
CGAGGTAATCGATCGCGCCCAAACCGGCCCGCAGGTCATCACCCGCCACGGCAAGCCCAATGCGGTCGTCGTTTCCGTCG
AGGAATGGGCGCGCAAGGTCGCTCGCAAAGGTACGCTCGCCGAATTCCTGCTGGCGTCGCCGCTTCGTGGCGCAGACCTT
GAGCTCGATCGCGTGCACGACACGCCACGCGACGAAATGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References