Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 501048..501589 Replicon chromosome
Accession NZ_CP030041
Organism Echinicola strongylocentroti strain MEBiC08714

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag DN752_RS01920 Protein ID WP_112782410.1
Coordinates 501287..501589 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag DN752_RS01915 Protein ID WP_112782409.1
Coordinates 501048..501290 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DN752_RS01885 496365..497300 + 936 WP_112782403.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
DN752_RS01890 497358..497741 + 384 WP_112782404.1 STAS domain-containing protein -
DN752_RS01895 497744..498655 + 912 WP_112782405.1 ribonuclease Z -
DN752_RS01900 498659..499459 + 801 WP_112782406.1 queuosine precursor transporter -
DN752_RS01905 499652..500056 + 405 WP_112782407.1 hypothetical protein -
DN752_RS01910 500098..500934 + 837 WP_162633077.1 hypothetical protein -
DN752_RS01915 501048..501290 + 243 WP_112782409.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
DN752_RS01920 501287..501589 + 303 WP_112782410.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DN752_RS01925 502108..502911 + 804 WP_112782411.1 AraC family transcriptional regulator -
DN752_RS01930 502995..503540 + 546 WP_112782412.1 cupin domain-containing protein -
DN752_RS01935 503605..504615 - 1011 WP_112782413.1 bile acid:sodium symporter -
DN752_RS01940 504747..505493 - 747 WP_112782414.1 RNA methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-94)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 12220.00 Da        Isoelectric Point: 9.8501

>T106894 WP_112782410.1 NZ_CP030041:501287-501589 [Echinicola strongylocentroti]
MSKNKYRISKQAIEDLNYIWVYTFHNWSKEQADRYYDLIIGEIEFIADNYLSGKSADQTRKNYRVTNIKSHLIFYRKVEN
EIVEITRILHQRMDIKKQLK

Download         Length: 303 bp

>T106894 NZ_CP030041:501287-501589 [Echinicola strongylocentroti]
ATGAGTAAAAACAAGTATCGAATAAGTAAACAAGCGATTGAAGATTTAAATTATATTTGGGTTTATACTTTTCACAATTG
GTCTAAAGAACAGGCAGATAGGTACTACGACTTAATAATCGGAGAGATTGAATTTATAGCGGACAACTATTTGAGTGGAA
AATCCGCGGATCAAACTCGAAAAAATTATCGAGTGACAAATATCAAGTCACATTTGATTTTTTACAGAAAAGTGGAAAAT
GAGATTGTTGAAATCACTAGAATTTTACATCAAAGAATGGACATTAAAAAACAACTGAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9269.38 Da        Isoelectric Point: 5.6744

>AT106894 WP_112782409.1 NZ_CP030041:501048-501290 [Echinicola strongylocentroti]
MGKNTSISLGNHFEEFIREEVNSGRYGSVSEVIRSALRLLEREEKKERELIKALEVGENSGFVEDFDPKQNLAELHRRHL

Download         Length: 243 bp

>AT106894 NZ_CP030041:501048-501290 [Echinicola strongylocentroti]
ATGGGAAAAAACACATCAATATCACTCGGAAATCATTTTGAGGAGTTTATCAGAGAAGAAGTAAATTCTGGTAGGTATGG
TTCAGTTAGCGAAGTTATTCGTTCCGCATTACGTTTGTTAGAACGTGAAGAAAAAAAGGAAAGAGAATTGATTAAAGCTC
TCGAAGTTGGAGAAAATAGCGGGTTTGTTGAAGATTTCGATCCAAAACAGAATCTGGCTGAATTACATCGTCGACACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References