Detailed information of TA system TA106891

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PumAB/upstrm_HI1419-dnstrm_HI1420
• Location: 2469038..2469621
• Replicon: chromosome
• Accession: NZ_CP030037
• Organism: Bradyrhizobium sp. CCBAU 51753

Toxin (Protein)

• Gene name: PumA
• Uniprot ID: -
• Locus tag: XH93_RS11095
• Protein ID: WP_194473517.1
• Coordinates: 2469328..2469621 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: PumB
• Uniprot ID: -
• Locus tag: XH93_RS11090
• Protein ID: WP_194473516.1
• Coordinates: 2469038..2469322 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XH93_RS11050	2464197..2464445	+	249	WP_194473509.1	hypothetical protein	-
XH93_RS11055	2464554..2464841	+	288	WP_194473510.1	hypothetical protein	-
XH93_RS11060	2465102..2465767	-	666	WP_194473511.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
XH93_RS11065	2466087..2466530	-	444	Protein_2193	DNA-binding protein	-
XH93_RS11070	2467059..2467547	+	489	WP_194473512.1	hypothetical protein	-
XH93_RS11075	2467544..2468446	-	903	WP_194473513.1	hypothetical protein	-
XH93_RS11080	2468463..2468711	+	249	WP_194473514.1	hypothetical protein	-
XH93_RS11085	2468708..2468992	+	285	WP_194473515.1	hypothetical protein	-
XH93_RS11090	2469038..2469322	-	285	WP_194473516.1	putative addiction module antidote protein	Antitoxin
XH93_RS11095	2469328..2469621	-	294	WP_194473517.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XH93_RS11100	2469688..2470062	+	375	WP_194475100.1	hypothetical protein	-
XH93_RS11105	2469947..2470685	+	739	Protein_2201	terminase family protein	-
XH93_RS41860	2470703..2471089	+	387	WP_210340475.1	terminase family protein	-
XH93_RS41865	2471132..2471425	+	294	WP_210340506.1	hypothetical protein	-
XH93_RS11115	2471425..2471637	+	213	WP_194473518.1	hypothetical protein	-
XH93_RS11120	2471705..2471983	-	279	WP_194473519.1	hypothetical protein	-
XH93_RS41870	2472225..2472530	-	306	WP_210340476.1	hypothetical protein	-
XH93_RS11125	2472530..2472739	-	210	WP_194473520.1	hypothetical protein	-
XH93_RS11130	2473081..2474559	-	1479	WP_194473521.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2469038..2487959	18921

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (13-91)

Antitoxin

• Uncharacterized protein HI1420 (4-92)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10932.54 Da
• Isoelectric Point: 9.9554

>T106891 WP_194473517.1 NZ_CP030037:c2469621-2469328 [Bradyrhizobium sp. CCBAU 51753]
MIEIRRTEAFTNWFDGLRDDRARDRIAARIARVASGLLGDVKPVGEGVSELRIDYGPGYRVYFTQRGRTIIILLCGGDKQ
TQSKDIKTAKKMASELE

Nucleotide

• Length: 294 bp

>T106891 NZ_CP030037:c2469621-2469328 [Bradyrhizobium sp. CCBAU 51753]
ATGATCGAAATCCGGCGCACAGAAGCTTTCACGAACTGGTTTGACGGTCTCCGCGATGATCGTGCCCGTGACCGGATTGC
CGCCCGGATCGCCCGCGTTGCTTCAGGCCTTTTGGGTGACGTGAAGCCGGTTGGCGAAGGCGTCTCGGAACTCAGGATCG
ACTACGGCCCCGGATATCGGGTTTACTTCACCCAGCGCGGGCGGACGATCATCATCCTGCTCTGCGGTGGCGACAAGCAG
ACCCAAAGCAAGGACATCAAGACCGCCAAGAAAATGGCCTCTGAACTGGAGTAA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10005.48 Da
• Isoelectric Point: 6.4649

>AT106891 WP_194473516.1 NZ_CP030037:c2469322-2469038 [Bradyrhizobium sp. CCBAU 51753]
MPIKTTKWNLEEHFTTPESQRALLDDALETGDAGHIANAIGIIARARGITEVAEQAGVTRMALYKGLTKDGDPKLSTVLG
VLEALGYKLTAKAA

Nucleotide

• Length: 285 bp

>AT106891 NZ_CP030037:c2469322-2469038 [Bradyrhizobium sp. CCBAU 51753]
ATGCCTATCAAAACCACCAAGTGGAATCTTGAAGAGCACTTCACCACCCCGGAAAGTCAACGTGCCCTGCTAGATGACGC
GCTCGAGACTGGCGACGCCGGCCATATTGCGAATGCCATCGGCATCATCGCTCGCGCGAGAGGCATAACGGAAGTCGCCG
AACAGGCTGGCGTAACCAGGATGGCCCTATACAAGGGGCTCACGAAGGATGGGGACCCAAAGCTCTCTACAGTTCTGGGA
GTGCTGGAAGCGCTGGGATATAAATTGACCGCGAAGGCGGCCTAG