Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2253008..2253681 Replicon chromosome
Accession NZ_CP030036
Organism Bradyrhizobium sp. CCBAU 21365

Toxin (Protein)


Gene name vapC Uniprot ID A0A7S7Q6D3
Locus tag XI02_RS10580 Protein ID WP_016846333.1
Coordinates 2253008..2253430 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A7S7Q682
Locus tag XI02_RS10585 Protein ID WP_016846334.1
Coordinates 2253427..2253681 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XI02_RS10570 2249051..2251840 + 2790 WP_016846331.1 autotransporter domain-containing protein -
XI02_RS10575 2251824..2252156 - 333 WP_016846332.1 hypothetical protein -
XI02_RS10580 2253008..2253430 - 423 WP_016846333.1 type II toxin-antitoxin system VapC family toxin Toxin
XI02_RS10585 2253427..2253681 - 255 WP_016846334.1 plasmid stabilization protein Antitoxin
XI02_RS10590 2254262..2254615 + 354 WP_129964841.1 DUF3883 domain-containing protein -
XI02_RS10595 2254720..2257683 + 2964 WP_129964842.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14769.94 Da        Isoelectric Point: 7.3188

>T106889 WP_016846333.1 NZ_CP030036:c2253430-2253008 [Bradyrhizobium sp. CCBAU 21365]
VILLDTNVVSEAMKPEPHPSVRHWLDAQAAETVFLSSVTVAELLFGIGALPRGRRKDRLAVALDGVLDLFTARILPFDTA
AARRYAELAVKARAAGKGFPTPDGYIAAIAAAHGFAVASRDTSAFNAAGLTIIDPWTATS

Download         Length: 423 bp

>T106889 NZ_CP030036:c2253430-2253008 [Bradyrhizobium sp. CCBAU 21365]
GTGATCCTGCTTGATACCAATGTGGTCTCCGAGGCGATGAAGCCCGAACCGCATCCATCGGTCCGCCACTGGCTCGACGC
CCAAGCGGCCGAGACGGTGTTTCTTTCCAGCGTTACCGTCGCCGAACTTTTGTTCGGTATCGGCGCGCTGCCGCGCGGCA
GGCGCAAGGACAGGCTGGCAGTTGCGCTCGACGGCGTGCTGGACCTTTTCACGGCCCGCATCCTGCCCTTCGATACCGCC
GCGGCGCGGCGCTATGCCGAACTCGCCGTTAAGGCGCGCGCGGCCGGAAAAGGCTTCCCCACGCCCGATGGCTACATCGC
CGCGATCGCCGCCGCCCACGGCTTCGCGGTGGCATCGCGCGACACGAGTGCGTTCAATGCTGCCGGTCTGACGATAATCG
ATCCCTGGACTGCAACCAGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9276.61 Da        Isoelectric Point: 9.0496

>AT106889 WP_016846334.1 NZ_CP030036:c2253681-2253427 [Bradyrhizobium sp. CCBAU 21365]
MAAVTIRNLSEEAHRALKVRAAQHNRSAEAEMRAILEAAVRPQGRLRLGTALSEMSRKIGLTNADVEALEHGRDVRPAEP
MHLE

Download         Length: 255 bp

>AT106889 NZ_CP030036:c2253681-2253427 [Bradyrhizobium sp. CCBAU 21365]
ATGGCCGCTGTCACCATCCGCAACCTCTCTGAGGAGGCGCATCGCGCCCTGAAAGTCCGTGCGGCGCAGCACAATCGCAG
CGCGGAAGCGGAAATGCGCGCCATTCTGGAGGCCGCCGTGCGTCCCCAGGGCCGGCTGCGGCTAGGCACCGCCCTTTCGG
AGATGAGCCGCAAGATTGGCCTCACCAATGCCGATGTCGAGGCACTTGAACATGGGCGCGACGTGCGTCCCGCTGAGCCG
ATGCACCTCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7S7Q6D3

Antitoxin

Source ID Structure
AlphaFold DB A0A7S7Q682

References