Detailed information of TA system TA106887

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2682798..2683434
• Replicon: chromosome
• Accession: NZ_CP030031
• Organism: Acinetobacter radioresistens strain LH6

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: A0A8H2JZL1
• Locus tag: DOM24_RS12590
• Protein ID: WP_034669920.1
• Coordinates: 2682798..2683184 (-)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: DOM24_RS12595
• Protein ID: WP_111282399.1
• Coordinates: 2683177..2683434 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DOM24_RS12575	2678094..2680373	-	2280	WP_111282395.1	TRAP transporter large permease subunit	-
DOM24_RS12580	2680532..2681125	-	594	WP_005024454.1	rhombosortase	-
DOM24_RS12585	2681203..2682318	-	1116	WP_005024452.1	hypothetical protein	-
DOM24_RS12590	2682798..2683184	-	387	WP_034669920.1	hypothetical protein	Toxin
DOM24_RS12595	2683177..2683434	-	258	WP_111282399.1	succinate dehydrogenase assembly factor 2	Antitoxin
DOM24_RS12600	2683618..2684790	+	1173	WP_005018376.1	acyl-CoA dehydrogenase family protein	-
DOM24_RS12605	2684844..2686334	-	1491	WP_111282401.1	NAD(P)/FAD-dependent oxidoreductase	-
DOM24_RS12610	2686515..2686892	-	378	WP_005018373.1	50S ribosomal protein L17	-
DOM24_RS12615	2686911..2687918	-	1008	WP_005018365.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15220.66 Da
• Isoelectric Point: 10.2575

>T106887 WP_034669920.1 NZ_CP030031:c2683184-2682798 [Acinetobacter radioresistens]
MVKQCFKLKPSRMAIMVQLSLLLGLLILFYSLLPLGLWLLCSVIGLISYSLFLKTPRPVRFEYLDAEEWTLQFCKAKHLD
RVVIRKIIDHQLYIVIYFQKNQVKPLVIWSDQLSLVYWKKLKMLAKLY

Nucleotide

• Length: 387 bp

>T106887 NZ_CP030031:c2683184-2682798 [Acinetobacter radioresistens]
ATGGTTAAGCAGTGTTTTAAGCTGAAACCTAGCCGCATGGCTATTATGGTTCAGCTTTCTTTACTACTCGGTTTGCTGAT
TTTGTTCTATTCACTACTACCGTTGGGACTATGGCTACTCTGTTCTGTCATTGGTTTGATAAGTTATAGCTTATTTTTAA
AAACGCCGCGTCCTGTACGCTTTGAATATCTAGATGCTGAAGAATGGACTCTTCAGTTCTGTAAAGCTAAACACTTAGAT
CGTGTTGTGATTCGAAAGATAATTGATCATCAACTTTATATTGTAATTTATTTTCAGAAAAATCAGGTTAAACCCTTGGT
TATCTGGAGTGATCAATTGTCTCTTGTATACTGGAAAAAATTAAAAATGTTAGCCAAGCTGTATTAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10237.75 Da
• Isoelectric Point: 4.5925

>AT106887 WP_111282399.1 NZ_CP030031:c2683434-2683177 [Acinetobacter radioresistens]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKQYYLQADVEEKATFAELVAQEDPDLLDWFMEVSEPPRPEMKQLIIKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT106887 NZ_CP030031:c2683434-2683177 [Acinetobacter radioresistens]
ATGTCTGAAGAAATGACTTTGGAAGAACGTAAAGTAATTTACCGTGCACGCCGGGGACTAAAAGAAATTGATGTATATTT
TGACCCTTATGTAAAACAATATTATTTACAAGCTGATGTGGAAGAAAAGGCCACCTTCGCCGAGCTCGTCGCACAGGAAG
ACCCTGATCTTCTAGACTGGTTTATGGAGGTTTCTGAACCCCCACGTCCGGAGATGAAACAGCTAATTATTAAACTTAAA
CATTATGTCCATGGTTAA