Detailed information of TA system TA106832

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 13967..14492
• Replicon: plasmid pSA20121591.1
• Accession: NZ_CP029990
• Organism: Salmonella enterica subsp. diarizonae serovar 48:i:z strain SA20121591

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: DOE59_RS25780
• Protein ID: WP_154715041.1
• Coordinates: 13967..14272 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: -
• Locus tag: DOE59_RS25785
• Protein ID: WP_080102268.1
• Coordinates: 14274..14492 (-)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DOE59_RS25750	9013..9351	-	339	WP_024262131.1	hypothetical protein	-
DOE59_RS25755	9443..10084	-	642	WP_000511281.1	ParA family protein	-
DOE59_RS25760	10601..11485	+	885	WP_154715039.1	RepB family plasmid replication initiator protein	-
DOE59_RS25765	11713..12495	-	783	WP_000082171.1	site-specific integrase	-
DOE59_RS25770	12530..13678	-	1149	WP_154715040.1	3'-5' exonuclease	-
DOE59_RS25775	13675..13965	-	291	WP_080102270.1	cytoplasmic protein	-
DOE59_RS25780	13967..14272	-	306	WP_154715041.1	type II toxin-antitoxin system toxin CcdB	Toxin
DOE59_RS25785	14274..14492	-	219	WP_080102268.1	type II toxin-antitoxin system antitoxin CcdA	Antitoxin
DOE59_RS25790	15087..15344	+	258	WP_154715042.1	hypothetical protein	-
DOE59_RS25795	15344..16300	+	957	WP_154715043.1	hypothetical protein	-
DOE59_RS25800	16334..16471	+	138	WP_154715044.1	hypothetical protein	-
DOE59_RS25805	16666..18018	-	1353	WP_154715045.1	hypothetical protein	-
DOE59_RS25810	18344..18880	-	537	WP_080102288.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..121189	121189

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (9-125)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-57)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 15030.03 Da
• Isoelectric Point: 5.5500

>T106832 WP_154715041.1 NZ_CP029990:c14272-13967 [Salmonella enterica subsp. diarizonae serovar 48:i:z]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 306 bp

>T106832 NZ_CP029990:c14272-13967 [Salmonella enterica subsp. diarizonae serovar 48:i:z]
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Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 10761.91 Da
• Isoelectric Point: 5.5500

>AT106832 WP_080102268.1 NZ_CP029990:c14492-14274 [Salmonella enterica subsp. diarizonae serovar 48:i:z]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 219 bp

>AT106832 NZ_CP029990:c14492-14274 [Salmonella enterica subsp. diarizonae serovar 48:i:z]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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