Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 2244775..2245300 Replicon chromosome
Accession NZ_CP029985
Organism Sphingomonas sp. FARSPH

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag DM480_RS10700 Protein ID WP_115381171.1
Coordinates 2245013..2245300 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag DM480_RS10695 Protein ID WP_115378909.1
Coordinates 2244775..2245023 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DM480_RS10665 2239890..2240315 - 426 WP_198665799.1 DUF4112 domain-containing protein -
DM480_RS10670 2240322..2241767 - 1446 WP_115378903.1 ABC transporter substrate-binding protein -
DM480_RS10675 2241983..2242177 + 195 WP_115378905.1 hypothetical protein -
DM480_RS10685 2242377..2242655 - 279 WP_115381169.1 integration host factor subunit beta -
DM480_RS10690 2242787..2244496 - 1710 WP_115378908.1 30S ribosomal protein S1 -
DM480_RS10695 2244775..2245023 + 249 WP_115378909.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
DM480_RS10700 2245013..2245300 + 288 WP_115381171.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DM480_RS10705 2245297..2245920 - 624 WP_115381173.1 (d)CMP kinase -
DM480_RS10710 2245917..2247299 - 1383 WP_115378911.1 3-phosphoshikimate 1-carboxyvinyltransferase -
DM480_RS10715 2247428..2247751 + 324 WP_115378913.1 TIGR02300 family protein -
DM480_RS10725 2248039..2248746 - 708 WP_115378915.1 FadR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10911.18 Da        Isoelectric Point: 4.8452

>T106830 WP_115381171.1 NZ_CP029985:2245013-2245300 [Sphingomonas sp. FARSPH]
MSFRVTPRADEDYYAIYAHGVERFGRAQAEAYADRLDESFAFLADHPRAARMRYEFDPPVRALPVGAHMIVYDVEPDDTV
VILRIPHGRADWAND

Download         Length: 288 bp

>T106830 NZ_CP029985:2245013-2245300 [Sphingomonas sp. FARSPH]
ATGTCTTTTAGGGTCACGCCGCGGGCGGACGAGGATTATTACGCCATCTATGCCCATGGCGTAGAACGGTTCGGCCGCGC
GCAGGCGGAAGCCTATGCCGACCGACTTGACGAGAGTTTCGCGTTTCTCGCGGATCATCCTCGGGCGGCGCGGATGCGCT
ACGAGTTCGATCCACCCGTTCGGGCGTTGCCGGTCGGTGCGCATATGATCGTCTACGACGTCGAGCCAGACGACACCGTT
GTCATCCTGCGCATTCCCCACGGCCGCGCCGACTGGGCAAACGACTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9210.43 Da        Isoelectric Point: 6.3543

>AT106830 WP_115378909.1 NZ_CP029985:2244775-2245023 [Sphingomonas sp. FARSPH]
MATMNISLPDAMKEWVEAQAETGRYANSSDVVRDLIRREQVRAEKIAAMQKMVDEGRASGISTLTPDERRAEARRRAGVD
VF

Download         Length: 249 bp

>AT106830 NZ_CP029985:2244775-2245023 [Sphingomonas sp. FARSPH]
ATGGCCACCATGAACATCTCGCTGCCAGACGCCATGAAGGAATGGGTCGAGGCACAGGCCGAAACCGGCCGTTACGCCAA
TTCCAGCGACGTCGTTCGCGACCTCATTCGCCGCGAGCAAGTGCGCGCCGAAAAGATCGCAGCGATGCAGAAGATGGTCG
ACGAAGGCCGGGCGAGCGGTATTTCCACGCTGACGCCGGACGAGCGGCGTGCCGAAGCGCGTCGACGCGCAGGTGTCGAT
GTCTTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References