Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 2327083..2327596 Replicon chromosome
Accession NZ_CP029983
Organism Pseudomonas sp. LG1E9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DNK50_RS10930 Protein ID WP_112193992.1
Coordinates 2327083..2327367 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DNK50_RS10935 Protein ID WP_112196918.1
Coordinates 2327357..2327596 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DNK50_RS10910 2323265..2324206 + 942 WP_112193990.1 hydroxymethylglutaryl-CoA lyase -
DNK50_RS10915 2324265..2325593 + 1329 WP_099587531.1 MFS transporter -
DNK50_RS10920 2325601..2326086 - 486 WP_099587530.1 DMT family transporter -
DNK50_RS10925 2326155..2327072 + 918 WP_099587529.1 LysR family transcriptional regulator -
DNK50_RS10930 2327083..2327367 - 285 WP_112193992.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DNK50_RS10935 2327357..2327596 - 240 WP_112196918.1 ribbon-helix-helix protein, CopG family Antitoxin
DNK50_RS10940 2327697..2328107 + 411 WP_099587526.1 fosfomycin resistance glutathione transferase -
DNK50_RS10945 2328162..2328803 + 642 WP_099587525.1 LysE family translocator -
DNK50_RS10950 2328923..2329450 + 528 WP_016975135.1 DUF4142 domain-containing protein -
DNK50_RS10955 2329505..2329930 - 426 WP_099587524.1 low affinity iron permease family protein -
DNK50_RS10960 2330108..2330890 + 783 WP_112193994.1 GNAT family N-acetyltransferase -
DNK50_RS10965 2330891..2331391 - 501 WP_099587522.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
DNK50_RS10970 2331480..2332397 - 918 WP_112193996.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-83)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11011.70 Da        Isoelectric Point: 9.6932

>T106827 WP_112193992.1 NZ_CP029983:c2327367-2327083 [Pseudomonas sp. LG1E9]
MQVEWLRVALRNLDDEAAFIAEENPKAAYEFVQAILSGLENIAQFPAMGKEGRVSGTREWVVPRWPYIVPYRIREGRLQV
MRIFHTRRQPPASW

Download         Length: 285 bp

>T106827 NZ_CP029983:c2327367-2327083 [Pseudomonas sp. LG1E9]
ATGCAGGTTGAGTGGCTGAGGGTAGCCCTCAGGAACCTTGACGACGAAGCGGCCTTCATTGCCGAAGAAAATCCCAAAGC
GGCCTATGAGTTCGTCCAGGCAATTTTGAGCGGCCTTGAGAACATCGCGCAATTTCCCGCAATGGGGAAAGAGGGCCGAG
TATCCGGTACTCGCGAATGGGTGGTGCCTCGATGGCCTTATATCGTTCCCTACCGCATTCGAGAGGGGCGGTTGCAGGTC
ATGCGGATTTTCCATACCCGTCGTCAGCCACCCGCGTCTTGGTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8653.83 Da        Isoelectric Point: 4.7863

>AT106827 WP_112196918.1 NZ_CP029983:c2327596-2327357 [Pseudomonas sp. LG1E9]
MSVMSLRIPEEIADTLASLAKATGRSKSFLAVDALREYLTREAWQIEEIQKALKEADAGDFATAAEVKAIADKWRNNAG

Download         Length: 240 bp

>AT106827 NZ_CP029983:c2327596-2327357 [Pseudomonas sp. LG1E9]
ATGTCTGTTATGTCCCTACGCATACCGGAAGAAATCGCCGATACGCTTGCCAGTCTTGCCAAGGCCACCGGGCGCAGCAA
ATCCTTTCTCGCAGTTGATGCGTTACGCGAATACTTGACGCGCGAAGCCTGGCAAATTGAAGAAATTCAAAAAGCCCTCA
AAGAAGCTGATGCGGGTGACTTCGCAACGGCAGCAGAGGTAAAAGCTATCGCCGACAAATGGCGCAACAATGCAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References