Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1405157..1405660 Replicon chromosome
Accession NZ_CP029983
Organism Pseudomonas sp. LG1E9

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag DNK50_RS06590 Protein ID WP_112193195.1
Coordinates 1405451..1405660 (-) Length 70 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DNK50_RS06585 Protein ID WP_112193193.1
Coordinates 1405157..1405447 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DNK50_RS06565 1401573..1403615 - 2043 WP_112193187.1 TonB-dependent copper receptor -
DNK50_RS06570 1403709..1404122 - 414 WP_112193189.1 DUF2946 domain-containing protein -
DNK50_RS06575 1404134..1404616 - 483 WP_099583620.1 copper chaperone PCu(A)C -
DNK50_RS06580 1404664..1405059 - 396 WP_112193191.1 DUF2946 domain-containing protein -
DNK50_RS06585 1405157..1405447 - 291 WP_112193193.1 putative addiction module antidote protein Antitoxin
DNK50_RS06590 1405451..1405660 - 210 WP_112193195.1 hypothetical protein Toxin
DNK50_RS06595 1406137..1406856 - 720 WP_112193197.1 cobalt-precorrin-6A reductase -
DNK50_RS06600 1406853..1408058 - 1206 WP_112193199.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
DNK50_RS06605 1408181..1409443 + 1263 WP_112193201.1 precorrin-3B synthase -
DNK50_RS06610 1409436..1410062 + 627 WP_099583613.1 precorrin-8X methylmutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-62)

Antitoxin

Uncharacterized protein HI1420

(6-95)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 7695.75 Da        Isoelectric Point: 8.9319

>T106826 WP_112193195.1 NZ_CP029983:c1405660-1405451 [Pseudomonas sp. LG1E9]
MAEAGNFGDCEPVGDGVSEMRIHYGPGYRVYFTRRNKVVYLLLIGGDKSTQSRDITRAKQMALNLGNKE

Download         Length: 210 bp

>T106826 NZ_CP029983:c1405660-1405451 [Pseudomonas sp. LG1E9]
ATGGCTGAAGCCGGAAACTTCGGTGACTGTGAGCCCGTAGGTGATGGGGTGTCCGAGATGCGAATCCATTACGGTCCTGG
GTATCGCGTTTACTTCACTCGTAGAAACAAGGTGGTTTATCTGTTGCTGATCGGTGGTGACAAATCAACACAAAGTCGGG
ACATAACGCGTGCAAAACAAATGGCACTAAATCTCGGCAATAAGGAGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10433.05 Da        Isoelectric Point: 5.8124

>AT106826 WP_112193193.1 NZ_CP029983:c1405447-1405157 [Pseudomonas sp. LG1E9]
MSESFTRFDAAKYLKTPLEMAAYLETCFEDDAGDGLLIRTALNDIARAQGMTQIARDAGLGRESLYKALSSTGNPEFATI
MKVMKALGLKLHVTAV

Download         Length: 291 bp

>AT106826 NZ_CP029983:c1405447-1405157 [Pseudomonas sp. LG1E9]
ATGAGCGAATCTTTTACCCGCTTTGACGCGGCAAAATATTTGAAAACCCCTTTGGAAATGGCTGCATACCTGGAGACCTG
CTTTGAAGACGATGCAGGCGATGGTCTTTTGATTCGTACCGCTCTCAATGATATCGCCCGCGCCCAAGGCATGACCCAAA
TTGCTCGCGACGCCGGCCTCGGACGCGAAAGCTTATATAAAGCCCTCTCCAGCACTGGCAATCCCGAGTTCGCGACTATC
ATGAAAGTGATGAAAGCGTTGGGCCTCAAGCTTCACGTCACGGCGGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References