Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 149506..150097 Replicon plasmid unnamed2
Accession NZ_CP029776
Organism Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag DM785_RS17130 Protein ID WP_110832813.1
Coordinates 149744..150097 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag DM785_RS17125 Protein ID WP_110832811.1
Coordinates 149506..149757 (+) Length 84 a.a.

Genomic Context

DM785_RS17085DM785_RS17090DM785_RS19735DM785_RS19740DM785_RS17115DM785_RS17125DM785_RS17130DM785_RS17135DM785_RS17150DM785_RS17160DM785_RS17165DM785_RS17095DM785_RS17100DM785_RS17120DM785_RS17140DM785_RS17145DM785_RS17155
Location: 144789..145186 (398 bp)
Type: Others
Protein ID: Protein_100
Location: 145164..145905 (742 bp)
Type: Others
Protein ID: Protein_101
Location: 146635..147504 (870 bp)
Type: Others
Protein ID: WP_204354206.1
Location: 147434..147943 (510 bp)
Type: Others
Protein ID: WP_204354210.1
Location: 147962..148171 (210 bp)
Type: Others
Protein ID: WP_162621486.1
Location: 149506..149757 (252 bp)
Type: Antitoxin
Protein ID: WP_110832811.1
Location: 149744..150097 (354 bp)
Type: Toxin
Protein ID: WP_110832813.1
Location: 150560..151651 (1092 bp)
Type: Others
Protein ID: WP_110827773.1
Location: 153047..153382 (336 bp)
Type: Others
Protein ID: WP_110832820.1
Location: 154071..154277 (207 bp)
Type: Others
Protein ID: WP_110832824.1
Location: 154400..155080 (681 bp)
Type: Others
Protein ID: WP_110832826.1
Location: 145965..146093 (129 bp)
Type: Others
Protein ID: WP_110832803.1
Location: 146087..146392 (306 bp)
Type: Others
Protein ID: WP_162621485.1
Location: 148427..149377 (951 bp)
Type: Others
Protein ID: WP_110832809.1
Location: 151631..152020 (390 bp)
Type: Others
Protein ID: WP_162621487.1
Location: 152090..152806 (717 bp)
Type: Others
Protein ID: WP_162621488.1
Location: 153452..153844 (393 bp)
Type: Others
Protein ID: WP_162621489.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DM785_RS17085144789..145186+398Protein_100MerR family DNA-binding protein-
DM785_RS17090145164..145905+742Protein_101MBL fold metallo-hydrolase-
DM785_RS17095145965..146093-129WP_110832803.1SDR family oxidoreductase-
DM785_RS17100146087..146392-306WP_162621485.1SDR family oxidoreductase-
DM785_RS19735146635..147504+870WP_204354206.1type I restriction endonuclease subunit R-
DM785_RS19740147434..147943+510WP_204354210.1hypothetical protein-
DM785_RS17115147962..148171+210WP_162621486.1transposase-
DM785_RS17120148427..149377-951WP_110832809.1tyrosine-type recombinase/integrase-
DM785_RS17125149506..149757+252WP_110832811.1antitoxinAntitoxin
DM785_RS17130149744..150097+354WP_110832813.1type II toxin-antitoxin system PemK/MazF family toxinToxin
DM785_RS17135150560..151651+1092WP_110827773.1transposase-
DM785_RS17140151631..152020-390WP_162621487.1hypothetical protein-
DM785_RS17145152090..152806-717WP_162621488.1hypothetical protein-
DM785_RS17150153047..153382+336WP_110832820.1hypothetical protein-
DM785_RS17155153452..153844-393WP_162621489.1hypothetical protein-
DM785_RS17160154071..154277+207WP_110832824.1hypothetical protein-
DM785_RS17165154400..155080+681WP_110832826.1SMI1/KNR4 family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..187951187951
-flankIS/Tn--143601..1446921091
-flankIS/Tn--150560..1516511091


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 12851.79 Da        Isoelectric Point: 9.8828

>T106724 WP_110832813.1 NZ_CP029776:149744-150097 [Deinococcus actinosclerus]
MRRGDLYLADLDPARPSEADKRRPVVIVSSDAMNRTVDRLGAGAVTVVPVTSNVTRIYDFQVLLPAERTGLTQDSKAQAE
QIRTISFSRLSAAPIGVVPPELMRRLDDALRLHLALT

Download         Length: 354 bp

>T106724 NZ_CP029776:149744-150097 [Deinococcus actinosclerus]
ATGCGCCGAGGTGATCTCTACCTCGCCGATCTGGACCCGGCCCGACCCAGCGAAGCCGACAAGCGGCGGCCCGTCGTCAT
CGTCAGCAGCGACGCCATGAACCGCACTGTTGATCGTCTGGGCGCCGGGGCCGTCACCGTGGTGCCCGTCACCTCGAATG
TCACCCGGATCTACGATTTCCAGGTGCTGCTCCCAGCAGAGCGAACGGGCCTGACTCAGGACAGCAAAGCGCAGGCGGAG
CAGATCCGCACCATCAGTTTCAGTCGCCTGAGCGCTGCCCCCATCGGTGTGGTGCCACCAGAGCTGATGCGACGACTCGA
TGACGCGCTGCGGCTGCACCTCGCCCTGACGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9238.19 Da        Isoelectric Point: 4.4316

>AT106724 WP_110832811.1 NZ_CP029776:149506-149757 [Deinococcus actinosclerus]
MTVQKTSVSIDAQLLAFAEHYQVTHHLRSRSEVFAEALTLLRERELETQYAAALSEWHASDDEDLWDAVAGDLLTSGGPN
APR

Download         Length: 252 bp

>AT106724 NZ_CP029776:149506-149757 [Deinococcus actinosclerus]
ATGACTGTTCAGAAAACCAGTGTGAGCATTGATGCCCAGCTGTTGGCCTTCGCTGAGCACTACCAAGTCACCCACCACCT
CCGCTCCCGTTCCGAGGTGTTCGCTGAGGCCCTGACACTCCTGCGGGAACGAGAACTCGAAACGCAATACGCTGCGGCCC
TCAGCGAATGGCACGCCTCTGACGACGAGGACCTGTGGGATGCGGTCGCCGGTGACCTCCTGACCAGCGGAGGTCCGAAT
GCGCCGAGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References