Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4650807..4650947 Replicon chromosome
Accession NZ_CP029746
Organism Serratia marcescens strain AR_0122

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4650851..4650947 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4650807..4650947 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM369_RS22045 4646007..4646432 + 426 WP_033638066.1 RNA polymerase-binding protein DksA -
AM369_RS22050 4646625..4647578 + 954 WP_033646426.1 prolyl aminopeptidase -
AM369_RS22055 4647610..4647840 - 231 WP_033642715.1 DNA polymerase III subunit theta -
AM369_RS22060 4648186..4648704 + 519 WP_025302449.1 non-heme ferritin -
AM369_RS22065 4648998..4649414 + 417 WP_046686875.1 CopC domain-containing protein YobA -
AM369_RS22070 4649417..4650298 + 882 WP_033646425.1 copper homeostasis membrane protein CopD -
AM369_RS22075 4650368..4650709 + 342 WP_025302452.1 YebY family protein -
- 4650807..4650947 - 141 - - Antitoxin
- 4650851..4650947 + 97 - - Toxin
AM369_RS22080 4651200..4651604 + 405 WP_033646424.1 hypothetical protein -
AM369_RS22085 4651601..4651819 - 219 WP_033638114.1 hypothetical protein -
AM369_RS24535 4651883..4652047 - 165 WP_154067227.1 hypothetical protein -
AM369_RS22090 4652339..4652689 + 351 WP_033638116.1 DUF4377 domain-containing protein -
AM369_RS22095 4652873..4654072 + 1200 WP_033638117.1 trans-2-enoyl-CoA reductase family protein -
AM369_RS22100 4654300..4654518 + 219 WP_033646423.1 hypothetical protein -
AM369_RS22105 4654690..4654995 + 306 WP_033646422.1 hypothetical protein -
AM369_RS22110 4655039..4655374 + 336 WP_033638120.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T106659 NZ_CP029746:4650851-4650947 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT106659 NZ_CP029746:c4650947-4650807 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References