Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2846378..2846850 Replicon chromosome
Accession NZ_CP029746
Organism Serratia marcescens strain AR_0122

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AM369_RS13385 Protein ID WP_033649650.1
Coordinates 2846575..2846850 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AM369_RS13380 Protein ID WP_033649649.1
Coordinates 2846378..2846575 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM369_RS13350 2841571..2842839 + 1269 WP_043148323.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
AM369_RS13355 2842836..2844035 + 1200 WP_033636667.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
AM369_RS13360 2844071..2844634 - 564 WP_033636670.1 DcrB family lipoprotein -
AM369_RS13365 2844715..2845149 - 435 WP_033649647.1 GNAT family N-acetyltransferase -
AM369_RS13370 2845191..2845850 - 660 WP_033649648.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
AM369_RS13375 2846071..2846316 + 246 WP_025304890.1 sulfurtransferase TusA -
AM369_RS13380 2846378..2846575 + 198 WP_033649649.1 hypothetical protein Antitoxin
AM369_RS13385 2846575..2846850 + 276 WP_033649650.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
AM369_RS13390 2846910..2849228 - 2319 WP_048321227.1 zinc/cadmium/mercury/lead-transporting ATPase -
AM369_RS13395 2849910..2851373 + 1464 WP_033636674.1 serralysin family metalloprotease -
AM369_RS13400 2851429..2851806 + 378 WP_033649652.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10638.51 Da        Isoelectric Point: 11.2806

>T106654 WP_033649650.1 NZ_CP029746:2846575-2846850 [Serratia marcescens]
MLNIEWTRAARQDLAEIVGFIANDNPLAARKMKVLIMEAVIPAGRHPRIFRRGRVDGTHEIPLHPHYLLVYQVLETHIRA
LRVLHTRRQYP

Download         Length: 276 bp

>T106654 NZ_CP029746:2846575-2846850 [Serratia marcescens]
ATGCTCAACATCGAATGGACTCGAGCCGCACGTCAGGATCTGGCGGAGATTGTGGGATTCATCGCCAATGATAACCCTCT
GGCGGCCAGAAAAATGAAGGTTCTCATCATGGAGGCCGTCATTCCCGCCGGCAGACATCCTCGAATTTTCCGGCGCGGCA
GAGTGGACGGCACGCATGAAATCCCCCTACATCCCCATTATCTCCTGGTTTACCAGGTGCTGGAAACTCACATCCGGGCG
TTGCGGGTTTTACATACGCGCCGACAATATCCTTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7398.49 Da        Isoelectric Point: 4.4143

>AT106654 WP_033649649.1 NZ_CP029746:2846378-2846575 [Serratia marcescens]
MSILLLPTVAKMENEERTQGYERWFLERVQEAMDEPRPGIPHDDVMAEMDAVIAAAEARIKAKQA

Download         Length: 198 bp

>AT106654 NZ_CP029746:2846378-2846575 [Serratia marcescens]
ATGAGTATTTTACTACTGCCTACGGTTGCCAAGATGGAAAATGAGGAACGTACACAGGGCTATGAGCGCTGGTTTCTTGA
AAGAGTTCAGGAAGCCATGGATGAGCCGCGGCCCGGCATTCCTCATGATGACGTGATGGCTGAAATGGATGCTGTTATCG
CTGCTGCAGAAGCCAGGATCAAAGCGAAGCAGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References