Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3628037..3628694 Replicon chromosome
Accession NZ_CP029736
Organism Providencia rettgeri strain AR_0082

Toxin (Protein)


Gene name cptA Uniprot ID A0A6G6PHM2
Locus tag AM461_RS16750 Protein ID WP_042851636.1
Coordinates 3628037..3628447 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A6G6PHM9
Locus tag AM461_RS16755 Protein ID WP_004913039.1
Coordinates 3628428..3628694 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM461_RS16730 3623940..3625673 - 1734 WP_110732096.1 single-stranded-DNA-specific exonuclease RecJ -
AM461_RS16735 3625683..3626387 - 705 WP_110732285.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
AM461_RS16740 3626409..3627311 - 903 WP_109912915.1 site-specific tyrosine recombinase XerD -
AM461_RS16745 3627429..3627947 + 519 WP_004913034.1 flavodoxin FldB -
AM461_RS16750 3628037..3628447 - 411 WP_042851636.1 protein YgfX Toxin
AM461_RS16755 3628428..3628694 - 267 WP_004913039.1 FAD assembly factor SdhE Antitoxin
AM461_RS16760 3628942..3629925 + 984 WP_110732097.1 tRNA-modifying protein YgfZ -
AM461_RS16765 3629937..3630557 + 621 WP_109912916.1 HD domain-containing protein -
AM461_RS16770 3630802..3631698 + 897 WP_164528562.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15612.59 Da        Isoelectric Point: 10.7733

>T106572 WP_042851636.1 NZ_CP029736:c3628447-3628037 [Providencia rettgeri]
VVLWKSNLSISWKTQLFSTCVHGVIGMFLLLTPWSPGNSMIWLPLLVVVVASWAKSQKNISKIKGVAVLVNGNKLQWKKN
EWRILKAPWLTRYGILLTLEALQGKPQKIHLWVAKDALSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

>T106572 NZ_CP029736:c3628447-3628037 [Providencia rettgeri]
GTGGTCCTGTGGAAATCTAATCTCTCCATTTCATGGAAAACTCAATTGTTCTCAACCTGTGTTCATGGGGTCATTGGGAT
GTTTTTGCTTCTGACTCCATGGTCTCCTGGTAACTCAATGATATGGCTGCCGCTACTAGTGGTTGTCGTTGCGAGTTGGG
CAAAGAGTCAGAAAAATATCAGTAAAATAAAAGGGGTTGCTGTACTGGTTAATGGCAATAAGCTTCAGTGGAAGAAAAAC
GAGTGGCGAATACTGAAAGCACCTTGGCTTACTCGTTACGGTATATTGCTGACATTAGAAGCGTTACAAGGCAAACCGCA
AAAGATCCATTTATGGGTAGCTAAAGACGCACTTTCGGAGGAAAATTGGCGTAATTTAAACCAGTTATTGCTGCAATACC
CTGATATCTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10674.24 Da        Isoelectric Point: 4.8780

>AT106572 WP_004913039.1 NZ_CP029736:c3628694-3628428 [Providencia rettgeri]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDNLTTQDKQVFVRLLECADPDLFNWLMNHGRPDDDELFRMIKLIQEKN
KNRGPVEI

Download         Length: 267 bp

>AT106572 NZ_CP029736:c3628694-3628428 [Providencia rettgeri]
ATGGATATTGAGAATAAAGCGCGAATTCATTGGGCATGCCGCCGTGGTATGCGTGAATTAGATATTTCAATCATGCCGTT
TTTTGAGTATGAATATGATAACCTGACAACCCAAGATAAGCAGGTATTTGTTCGATTATTAGAATGTGCGGACCCTGACT
TATTCAACTGGTTAATGAATCATGGCCGCCCAGATGATGACGAACTTTTTCGTATGATTAAACTGATTCAGGAAAAAAAT
AAAAATCGTGGTCCTGTGGAAATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6G6PHM2

Antitoxin

Source ID Structure
AlphaFold DB A0A6G6PHM9

References