Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 894908..895454 Replicon chromosome
Accession NZ_CP029736
Organism Providencia rettgeri strain AR_0082

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AM461_RS03845 Protein ID WP_109912959.1
Coordinates 894908..895189 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AM461_RS03850 Protein ID WP_102140619.1
Coordinates 895170..895454 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM461_RS03830 891810..893180 - 1371 WP_004906999.1 envelope stress sensor histidine kinase CpxA -
AM461_RS03835 893177..893875 - 699 WP_004907000.1 envelope stress response regulator transcription factor CpxR -
AM461_RS03840 894026..894613 + 588 WP_004907001.1 Spy/CpxP family protein refolding chaperone -
AM461_RS03845 894908..895189 - 282 WP_109912959.1 type II toxin-antitoxin system YafQ family toxin Toxin
AM461_RS03850 895170..895454 - 285 WP_102140619.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
AM461_RS03855 895616..896197 + 582 WP_004907006.1 HutD family protein -
AM461_RS03865 896424..897176 + 753 WP_004907010.1 M48 family metallopeptidase -
AM461_RS03870 897414..898055 + 642 WP_110731554.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
AM461_RS03875 898052..898996 + 945 WP_109912960.1 phosphatidate cytidylyltransferase -
AM461_RS03880 899402..900379 + 978 WP_004265237.1 6-phosphofructokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(9-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10968.80 Da        Isoelectric Point: 9.1315

>T106570 WP_109912959.1 NZ_CP029736:c895189-894908 [Providencia rettgeri]
MLKIRVKSQFKKDLKKSLSDKKRNTQLLKELIDNHLCITGSVPAEYLPHPLKGNWRPCYEYHIQPDFLLIWDINYQTNEI
ILVRCGSHSELFG

Download         Length: 282 bp

>T106570 NZ_CP029736:c895189-894908 [Providencia rettgeri]
ATGCTGAAAATTCGCGTTAAATCCCAATTCAAAAAAGACTTAAAAAAGTCGTTATCTGACAAAAAAAGAAATACTCAGCT
ATTAAAAGAGCTAATCGATAACCACCTATGCATTACTGGCTCTGTTCCAGCAGAATATTTGCCTCATCCCTTAAAAGGAA
ACTGGAGACCTTGCTATGAATATCACATACAACCCGATTTTTTATTAATTTGGGATATAAACTACCAAACCAATGAAATC
ATATTAGTTCGCTGTGGTTCTCATTCTGAATTATTTGGCTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10420.71 Da        Isoelectric Point: 4.6412

>AT106570 WP_102140619.1 NZ_CP029736:c895454-895170 [Providencia rettgeri]
MASTQHKTDIVRARIEPKVRENAEAVLSELGISMSDAIRIFVKQISLRQAFPIELKTPNSITLEAINAPTTDETFDSAED
LFSQVSKSDAENSR

Download         Length: 285 bp

>AT106570 NZ_CP029736:c895454-895170 [Providencia rettgeri]
ATGGCCAGTACTCAACATAAAACAGATATTGTCAGAGCCAGAATTGAGCCTAAAGTCAGGGAAAATGCTGAAGCAGTGTT
ATCTGAATTAGGGATTAGCATGTCTGATGCTATTCGTATTTTCGTCAAGCAAATATCATTGCGACAAGCTTTTCCTATTG
AGTTAAAAACACCAAACTCAATTACATTAGAAGCTATTAATGCACCAACTACAGACGAAACATTTGACTCTGCTGAAGAT
TTATTTAGCCAAGTGAGCAAGTCCGATGCTGAAAATTCGCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References