Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 6462899..6463349 Replicon chromosome
Accession NZ_CP029693
Organism Pseudomonas putida strain JBC17

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DKY63_RS30370 Protein ID WP_110967506.1
Coordinates 6462899..6463168 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DKY63_RS30375 Protein ID WP_110967507.1
Coordinates 6463158..6463349 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DKY63_RS30345 6458370..6459008 - 639 WP_110967501.1 type 1 glutamine amidotransferase -
DKY63_RS30350 6459224..6460003 + 780 WP_110967502.1 ABC transporter substrate-binding protein -
DKY63_RS30355 6460205..6461317 + 1113 WP_110967503.1 succinylglutamate desuccinylase/aspartoacylase family protein -
DKY63_RS30360 6461507..6462223 + 717 WP_110967504.1 dienelactone hydrolase family protein -
DKY63_RS30365 6462227..6462796 - 570 WP_110967505.1 hypothetical protein -
DKY63_RS30370 6462899..6463168 - 270 WP_110967506.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DKY63_RS30375 6463158..6463349 - 192 WP_110967507.1 antitoxin Antitoxin
DKY63_RS30380 6463590..6463916 - 327 WP_110967508.1 antibiotic biosynthesis monooxygenase -
DKY63_RS30385 6463947..6464618 - 672 WP_110967509.1 glutathione S-transferase N-terminal domain-containing protein -
DKY63_RS30390 6464702..6465493 - 792 WP_110967510.1 hypothetical protein -
DKY63_RS30395 6465737..6467056 + 1320 WP_110967511.1 Nramp family divalent metal transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10423.05 Da        Isoelectric Point: 6.7228

>T106469 WP_110967506.1 NZ_CP029693:c6463168-6462899 [Pseudomonas putida]
MLVEWRPEARAELRQILMYIGDRNLAAAYELQQAIEIAVSALPEHPYLYRFGRLSGTREIVVHPNYLVVYQITDRIEIVS
VLHARQQYP

Download         Length: 270 bp

>T106469 NZ_CP029693:c6463168-6462899 [Pseudomonas putida]
ATGCTGGTTGAGTGGCGGCCCGAAGCGCGGGCCGAACTCCGGCAAATTCTGATGTATATCGGCGATCGTAATCTGGCAGC
AGCGTATGAGCTCCAACAAGCCATTGAGATTGCTGTATCGGCCCTTCCTGAACATCCCTATCTCTACCGATTTGGCCGAC
TATCCGGCACTCGCGAGATCGTTGTGCATCCCAACTACCTTGTGGTTTATCAAATAACGGATCGAATCGAGATCGTCAGT
GTTTTGCATGCCAGACAGCAATACCCCTGA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7222.07 Da        Isoelectric Point: 4.7023

>AT106469 WP_110967507.1 NZ_CP029693:c6463349-6463158 [Pseudomonas putida]
MSTELSPIVSEFETEEQAASYDRWFRAKVQASLDDPRPSIPHDQVMAEMQTLLEAKRKQRNAG

Download         Length: 192 bp

>AT106469 NZ_CP029693:c6463349-6463158 [Pseudomonas putida]
ATGAGCACCGAACTTTCCCCCATCGTTTCCGAATTTGAAACCGAAGAGCAAGCCGCCAGCTATGATCGCTGGTTCCGCGC
CAAGGTACAGGCTTCGCTGGATGATCCGCGCCCGAGCATTCCGCACGATCAGGTGATGGCTGAAATGCAAACCCTTCTTG
AGGCTAAGCGCAAACAGCGCAATGCTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References