106466

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 2892996..2893614 Replicon chromosome
Accession NZ_CP029693
Organism Pseudomonas putida strain JBC17

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag DKY63_RS13375 Protein ID WP_204354349.1
Coordinates 2892996..2893301 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag DKY63_RS13380 Protein ID WP_110964527.1
Coordinates 2893294..2893614 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DKY63_RS13345 2888471..2889034 + 564 WP_110964522.1 Bro-N domain-containing protein -
DKY63_RS13350 2889233..2890051 - 819 WP_110964523.1 HNH endonuclease -
DKY63_RS13355 2890260..2891218 + 959 Protein_2553 hypothetical protein -
DKY63_RS13360 2891249..2891944 - 696 WP_110964524.1 hypothetical protein -
DKY63_RS13365 2891980..2892348 - 369 WP_110967919.1 hypothetical protein -
DKY63_RS13370 2892575..2892892 + 318 WP_110964525.1 helix-turn-helix transcriptional regulator -
DKY63_RS13375 2892996..2893301 + 306 WP_204354349.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DKY63_RS13380 2893294..2893614 + 321 WP_110964527.1 helix-turn-helix domain-containing protein Antitoxin
DKY63_RS13385 2893642..2895150 - 1509 WP_110964528.1 amidase -
DKY63_RS13390 2895282..2896340 - 1059 WP_110964529.1 MBL fold metallo-hydrolase -
DKY63_RS13395 2896568..2897179 + 612 WP_110964530.1 TetR/AcrR family transcriptional regulator -
DKY63_RS13400 2897306..2897836 + 531 WP_110964531.1 DUF1003 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-88)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11018.47 Da        Isoelectric Point: 8.5100

>T106466 WP_204354349.1 NZ_CP029693:2892996-2893301 [Pseudomonas putida]
MPTDVQDVFGHALDLAQSGKKHSDAKPLRGFGSAGVLELIEDFNTNTYRAVYTVSFGSAIYVLHCFQKKSTTGIKTSQCD
IDLIRKRLQAAQDHAKGMSNG

Download         Length: 306 bp

>T106466 NZ_CP029693:2892996-2893301 [Pseudomonas putida]
ATGCCCACAGATGTACAGGATGTTTTTGGTCACGCTCTCGATCTGGCACAAAGCGGCAAGAAACATTCAGATGCCAAGCC
GCTAAGGGGCTTCGGAAGTGCTGGTGTCCTTGAGTTGATAGAGGACTTCAATACGAACACTTACCGCGCCGTTTACACAG
TCAGTTTCGGTAGCGCCATTTATGTTCTGCACTGCTTTCAGAAAAAGTCGACTACAGGTATCAAGACCTCGCAGTGCGAC
ATCGATCTGATCAGAAAGAGGCTACAAGCAGCGCAGGATCATGCGAAAGGAATGAGTAATGGTTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11727.70 Da        Isoelectric Point: 9.7890

>AT106466 WP_110964527.1 NZ_CP029693:2893294-2893614 [Pseudomonas putida]
MVDIEESSGNVYQDLGTPNASEMRVKSQLAAKIGEIIKARHLTQVQASEILGLSQPKLSEMLRGKFRGISEAKMMECLLL
LGRDVQIVVKSAPRSRKEGRLEVVFS

Download         Length: 321 bp

>AT106466 NZ_CP029693:2893294-2893614 [Pseudomonas putida]
ATGGTTGATATCGAAGAAAGCAGCGGCAACGTCTACCAAGACCTCGGAACCCCCAATGCCAGCGAAATGCGAGTCAAATC
CCAGCTGGCGGCAAAGATTGGGGAAATCATCAAGGCCCGTCATCTGACCCAGGTTCAGGCATCAGAAATTTTGGGGCTGT
CACAACCCAAGCTGTCCGAGATGTTGCGTGGAAAGTTTCGAGGAATCAGTGAGGCCAAGATGATGGAGTGCCTTCTGTTG
CTCGGGCGCGACGTGCAGATCGTCGTCAAATCGGCCCCCCGTTCACGCAAAGAGGGCCGTCTTGAGGTGGTCTTCAGTTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References