Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 176823..176968 Replicon chromosome
Accession NZ_CP029689
Organism Klebsiella pneumoniae strain 160111

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 176830..176932 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 176823..176968 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DL890_RS00890 172355..173788 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DL890_RS00895 173904..174143 + 240 WP_002911393.1 YebV family protein -
DL890_RS00900 174241..174432 + 192 WP_002911395.1 YebW family protein -
DL890_RS00905 174429..175082 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
DL890_RS00910 175239..176207 + 969 WP_004151446.1 VirK/YbjX family protein -
DL890_RS30185 176312..176455 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 176823..176968 + 146 - - Antitoxin
- 176830..176932 - 103 - - Toxin
DL890_RS00920 177091..177429 - 339 WP_002911404.1 YebY family protein -
DL890_RS00925 177446..178315 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
DL890_RS00930 178319..178693 - 375 WP_004151448.1 CopC domain-containing protein YobA -
DL890_RS00935 178806..179036 + 231 WP_002911406.1 DNA polymerase III subunit theta -
DL890_RS00940 179115..179774 + 660 WP_002911407.1 exodeoxyribonuclease X -
DL890_RS00945 179778..181838 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T106416 NZ_CP029689:c176932-176830 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT106416 NZ_CP029689:176823-176968 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References