Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 3422382..3422856 Replicon chromosome
Accession NZ_CP029642
Organism Arthrobacter dokdonellae isolate rhizosphere

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DMB86_RS15240 Protein ID WP_113718551.1
Coordinates 3422593..3422856 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag DMB86_RS15235 Protein ID WP_113718550.1
Coordinates 3422382..3422609 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DMB86_RS15210 3417809..3418198 - 390 WP_113718545.1 hypothetical protein -
DMB86_RS15215 3418685..3419722 - 1038 WP_113718546.1 LCP family protein -
DMB86_RS15220 3419870..3420367 + 498 WP_113718547.1 DUF3515 domain-containing protein -
DMB86_RS15225 3420364..3421530 - 1167 WP_113718548.1 class I SAM-dependent methyltransferase -
DMB86_RS15230 3421788..3422030 - 243 WP_113718549.1 hypothetical protein -
DMB86_RS15235 3422382..3422609 + 228 WP_113718550.1 ribbon-helix-helix protein, CopG family Antitoxin
DMB86_RS15240 3422593..3422856 + 264 WP_113718551.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DMB86_RS15245 3422926..3424068 - 1143 WP_113718552.1 D-alanine--D-alanine ligase -
DMB86_RS15250 3424072..3425841 - 1770 WP_113719607.1 NAD(P)-dependent glycerol-3-phosphate dehydrogenase -
DMB86_RS15255 3425960..3427297 - 1338 WP_113718553.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9870.37 Da        Isoelectric Point: 6.9784

>T106059 WP_113718551.1 NZ_CP029642:3422593-3422856 [Arthrobacter dokdonellae]
MAWKVEYDPDAVKALQRLDKAVARRIVDDLDDVAALEDPRSRAKALTGSLGGLWRYRVGDYRIICDVISEELVIVALDLG
HRSKIYR

Download         Length: 264 bp

>T106059 NZ_CP029642:3422593-3422856 [Arthrobacter dokdonellae]
TTGGCTTGGAAGGTTGAGTACGACCCGGACGCGGTGAAGGCCCTCCAACGACTCGACAAAGCCGTCGCCCGACGTATTGT
GGACGACCTCGATGACGTTGCTGCCCTCGAAGACCCACGCTCACGCGCCAAAGCACTCACCGGATCCTTGGGCGGCCTGT
GGCGTTACAGGGTTGGCGACTACCGCATCATCTGCGACGTGATCAGCGAGGAACTCGTCATCGTTGCCCTCGACCTCGGC
CATCGCTCAAAAATCTACCGGTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8551.70 Da        Isoelectric Point: 10.4023

>AT106059 WP_113718550.1 NZ_CP029642:3422382-3422609 [Arthrobacter dokdonellae]
MPTSVRLPPETEKRLDRLAASTGRTKAFYVRELIVSGLDRLEWEYSVAQNAHDIRAGRRRTIPSDEVRRSLGLEG

Download         Length: 228 bp

>AT106059 NZ_CP029642:3422382-3422609 [Arthrobacter dokdonellae]
ATGCCTACTTCGGTTCGTCTACCCCCGGAAACTGAAAAACGCCTCGACCGGTTGGCCGCTTCCACGGGCCGGACCAAGGC
GTTCTACGTTCGAGAACTCATCGTCTCCGGCCTCGACCGTCTGGAATGGGAATACTCCGTTGCGCAGAACGCGCACGACA
TTCGTGCCGGCCGCAGGCGGACCATCCCCAGTGACGAGGTAAGGCGCTCTCTTGGCTTGGAAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References