Detailed information of TA system TA106057

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2966697..2967216
• Replicon: chromosome
• Accession: NZ_CP029640
• Organism: Paraburkholderia dokdonella strain DCT13 isolate rhisosphere

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DMB87_RS13495
• Protein ID: WP_129563121.1
• Coordinates: 2966926..2967216 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: DMB87_RS13490
• Protein ID: WP_129563120.1
• Coordinates: 2966697..2966939 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DMB87_RS13470	2962403..2962564	-	162	Protein_2620	Fic family protein	-
DMB87_RS13475	2962662..2963393	-	732	WP_129563118.1	RNA polymerase sigma factor FliA	-
DMB87_RS13480	2963533..2964390	-	858	Protein_2622	MinD/ParA family protein	-
DMB87_RS13485	2964383..2966344	-	1962	WP_129563119.1	flagellar biosynthesis protein FlhF	-
DMB87_RS13490	2966697..2966939	+	243	WP_129563120.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
DMB87_RS13495	2966926..2967216	+	291	WP_129563121.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DMB87_RS13500	2967486..2969585	-	2100	WP_129563122.1	flagellar biosynthesis protein FlhA	-
DMB87_RS13505	2969582..2970898	-	1317	WP_129563123.1	flagellar type III secretion system protein FlhB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-75)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11134.07 Da
• Isoelectric Point: 10.4996

>T106057 WP_129563121.1 NZ_CP029640:2966926-2967216 [Paraburkholderia dokdonella]
MKTYELKFHKSALKDWQHLDSTVRTQLRKKLVERLIAPRVDSARLSSMPDCYKIKLAASGYRLVYQVIDGELVVLVIAIG
KREADQAYRKARTRLD

Nucleotide

• Length: 291 bp

>T106057 NZ_CP029640:2966926-2967216 [Paraburkholderia dokdonella]
TTGAAGACCTATGAGCTGAAGTTCCACAAATCCGCGCTTAAAGATTGGCAACACCTTGACTCCACAGTGCGTACGCAACT
CCGCAAAAAGCTCGTAGAGCGGCTGATTGCGCCTCGCGTAGATTCGGCGCGTCTCAGTAGCATGCCGGATTGCTACAAGA
TCAAACTGGCAGCGTCAGGCTATCGTCTCGTCTATCAGGTGATTGACGGAGAGCTCGTTGTTCTTGTGATTGCGATCGGC
AAGCGCGAGGCAGATCAAGCCTATCGCAAGGCACGCACTCGCCTGGATTAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8749.17 Da
• Isoelectric Point: 4.2472

>AT106057 WP_129563120.1 NZ_CP029640:2966697-2966939 [Paraburkholderia dokdonella]
MESILARVSIGISELKMNPMAAIEKADGPVAILNRNKPVAYLVPASEWEAICDRLEDIELAEIVKSRAGEEVVSVKLEDL

Nucleotide

• Length: 243 bp

>AT106057 NZ_CP029640:2966697-2966939 [Paraburkholderia dokdonella]
ATGGAAAGCATTCTGGCAAGAGTATCGATCGGTATTAGCGAGCTGAAAATGAACCCAATGGCAGCAATCGAAAAAGCCGA
CGGCCCCGTTGCAATCCTCAACCGGAACAAGCCGGTTGCCTATCTGGTCCCGGCCAGCGAATGGGAAGCGATCTGCGACC
GTCTCGAAGATATCGAGTTGGCCGAAATCGTGAAATCCCGCGCTGGCGAAGAAGTCGTGAGCGTCAAGCTTGAAGACCTA
TGA