Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 146396..148122 | Replicon | chromosome |
Accession | NZ_CP029640 | ||
Organism | Paraburkholderia dokdonella strain DCT13 isolate rhisosphere |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | DMB87_RS00705 | Protein ID | WP_129560964.1 |
Coordinates | 146396..147046 (+) | Length | 217 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | DMB87_RS00710 | Protein ID | WP_129560965.1 |
Coordinates | 147046..148122 (+) | Length | 359 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DMB87_RS00685 | 141526..141747 | + | 222 | WP_129560960.1 | DUF3018 family protein | - |
DMB87_RS00690 | 142285..142611 | + | 327 | WP_129560961.1 | helix-turn-helix domain-containing protein | - |
DMB87_RS00695 | 142650..145190 | + | 2541 | WP_129560962.1 | N-6 DNA methylase | - |
DMB87_RS00700 | 145183..146403 | + | 1221 | WP_160113433.1 | restriction endonuclease subunit S | - |
DMB87_RS00705 | 146396..147046 | + | 651 | WP_129560964.1 | DUF4433 domain-containing protein | Toxin |
DMB87_RS00710 | 147046..148122 | + | 1077 | WP_129560965.1 | macro domain-containing protein | Antitoxin |
DMB87_RS00715 | 148132..151395 | + | 3264 | WP_129560966.1 | type I restriction endonuclease subunit R | - |
DMB87_RS00720 | 151395..152102 | + | 708 | WP_129560967.1 | M48 family metallopeptidase | - |
DMB87_RS00725 | 152462..152551 | + | 90 | Protein_137 | DUF3387 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 217 a.a. Molecular weight: 25011.49 Da Isoelectric Point: 7.5708
>T106055 WP_129560964.1 NZ_CP029640:146396-147046 [Paraburkholderia dokdonella]
MANHYPNLNPDKALIWRIVHRDNLQWILDNGLHCGNSAVKAPGWVSIGNPELIDKRANHPVPRPPGGLLNDYVPFYFTPF
SPMLRNIHTGWGGIQKRSNEEIVILVSSLHHIAGQGLPFLFTDSHAYYQWANFYSDVAYLDKIDWPLLQRRDFKRDPDDP
AKFERYQAEALIHQHLPVSGLLGVVCYTEQLKQRIEQEIQVRNLNLPVYARTGWYF
MANHYPNLNPDKALIWRIVHRDNLQWILDNGLHCGNSAVKAPGWVSIGNPELIDKRANHPVPRPPGGLLNDYVPFYFTPF
SPMLRNIHTGWGGIQKRSNEEIVILVSSLHHIAGQGLPFLFTDSHAYYQWANFYSDVAYLDKIDWPLLQRRDFKRDPDDP
AKFERYQAEALIHQHLPVSGLLGVVCYTEQLKQRIEQEIQVRNLNLPVYARTGWYF
Download Length: 651 bp
>T106055 NZ_CP029640:146396-147046 [Paraburkholderia dokdonella]
ATGGCTAATCACTATCCCAACCTCAACCCTGACAAGGCCCTGATCTGGCGCATCGTTCACCGCGACAATCTGCAGTGGAT
TCTGGATAATGGCCTGCACTGTGGCAACAGCGCTGTGAAAGCGCCGGGCTGGGTGAGTATCGGTAACCCAGAACTGATCG
ACAAGCGTGCCAATCACCCGGTGCCGCGGCCACCGGGCGGCTTGCTGAACGACTACGTACCGTTCTACTTCACACCCTTT
TCGCCCATGCTGCGGAATATCCACACCGGCTGGGGCGGCATCCAGAAGCGATCGAACGAGGAAATCGTGATCCTGGTGTC
TAGTCTGCACCACATTGCCGGGCAAGGCTTGCCGTTTTTGTTTACCGATAGCCATGCCTATTACCAGTGGGCAAATTTTT
ACTCAGATGTGGCCTACCTCGACAAGATCGATTGGCCCTTGCTGCAACGGCGGGACTTCAAGCGCGACCCGGACGACCCT
GCCAAGTTTGAGCGCTATCAGGCCGAGGCGTTGATCCATCAACATTTGCCGGTGAGCGGACTTCTCGGCGTCGTGTGCTA
TACGGAACAATTGAAGCAACGCATTGAACAGGAGATTCAGGTCCGCAATCTGAACCTGCCGGTTTATGCCCGAACAGGGT
GGTATTTCTGA
ATGGCTAATCACTATCCCAACCTCAACCCTGACAAGGCCCTGATCTGGCGCATCGTTCACCGCGACAATCTGCAGTGGAT
TCTGGATAATGGCCTGCACTGTGGCAACAGCGCTGTGAAAGCGCCGGGCTGGGTGAGTATCGGTAACCCAGAACTGATCG
ACAAGCGTGCCAATCACCCGGTGCCGCGGCCACCGGGCGGCTTGCTGAACGACTACGTACCGTTCTACTTCACACCCTTT
TCGCCCATGCTGCGGAATATCCACACCGGCTGGGGCGGCATCCAGAAGCGATCGAACGAGGAAATCGTGATCCTGGTGTC
TAGTCTGCACCACATTGCCGGGCAAGGCTTGCCGTTTTTGTTTACCGATAGCCATGCCTATTACCAGTGGGCAAATTTTT
ACTCAGATGTGGCCTACCTCGACAAGATCGATTGGCCCTTGCTGCAACGGCGGGACTTCAAGCGCGACCCGGACGACCCT
GCCAAGTTTGAGCGCTATCAGGCCGAGGCGTTGATCCATCAACATTTGCCGGTGAGCGGACTTCTCGGCGTCGTGTGCTA
TACGGAACAATTGAAGCAACGCATTGAACAGGAGATTCAGGTCCGCAATCTGAACCTGCCGGTTTATGCCCGAACAGGGT
GGTATTTCTGA
Antitoxin
Download Length: 359 a.a. Molecular weight: 40517.49 Da Isoelectric Point: 6.5090
>AT106055 WP_129560965.1 NZ_CP029640:147046-148122 [Paraburkholderia dokdonella]
MITFTQGNLLEARAEALVNTVNTVGVMGKGIALMFKERFDENFRRYAAACKAKEVRTGKMFVTPVHELDGPHWIVNFPTK
QHWRAPSRMEWIIEGLQDLRHFLIEQQVKSIAIPPLGAGNGGLEWADVREQIELTLGDLDIDILVFEPTKQYQNVAKRAG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIERYNPGDNPLNLQFAPHKYGPYANRLDHLLNNLDGSYLH
SEKRISDADPLDVIWFDDERKTFVQTYLKSEARAYTQALESTAALIDGFESPFGMELLATVDWLLAREGVAPTVPALRKG
LRHWRGGPDAGARKDRLFDDRALGIALERLTQAAPAIT
MITFTQGNLLEARAEALVNTVNTVGVMGKGIALMFKERFDENFRRYAAACKAKEVRTGKMFVTPVHELDGPHWIVNFPTK
QHWRAPSRMEWIIEGLQDLRHFLIEQQVKSIAIPPLGAGNGGLEWADVREQIELTLGDLDIDILVFEPTKQYQNVAKRAG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIERYNPGDNPLNLQFAPHKYGPYANRLDHLLNNLDGSYLH
SEKRISDADPLDVIWFDDERKTFVQTYLKSEARAYTQALESTAALIDGFESPFGMELLATVDWLLAREGVAPTVPALRKG
LRHWRGGPDAGARKDRLFDDRALGIALERLTQAAPAIT
Download Length: 1077 bp
>AT106055 NZ_CP029640:147046-148122 [Paraburkholderia dokdonella]
ATGATTACATTCACTCAAGGCAATTTGTTGGAGGCTCGCGCTGAGGCTCTGGTCAACACTGTCAACACCGTTGGGGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGTTTTGACGAGAACTTCCGCCGTTACGCCGCCGCCTGCAAGGCCAAGG
AAGTACGGACTGGTAAGATGTTTGTGACGCCGGTGCACGAGCTGGATGGGCCGCACTGGATCGTCAACTTCCCCACCAAG
CAACACTGGCGCGCACCGTCGCGCATGGAATGGATCATTGAGGGCTTGCAGGATCTGAGGCACTTCTTGATCGAGCAACA
AGTTAAGTCCATCGCCATCCCGCCGCTGGGTGCCGGTAACGGTGGCCTGGAGTGGGCCGACGTGCGCGAGCAGATCGAGC
TGACATTGGGTGATCTGGACATCGACATCCTGGTGTTCGAGCCCACTAAGCAATACCAGAACGTAGCCAAGCGCGCCGGG
GTCGAGAAGCTAACGCCGGCCCGAGCGCTGATTGCCGAGCTGGTGCGGCGGTACTGGGTGTTGGGCATGGAATGCAGCCT
CCTGGAGATTCAGAAGCTGGCGTGGTTTCTGGAGCGTGCGATTGAGCGCTACAACCCGGGTGACAATCCGCTGAACCTGC
AGTTTGCACCGCACAAGTACGGGCCCTATGCCAACCGGCTCGACCACCTACTGAACAATCTGGATGGCAGCTATTTGCAC
TCGGAGAAGCGCATCAGCGACGCCGATCCCCTAGATGTGATCTGGTTTGACGACGAGCGCAAGACTTTTGTGCAGACCTA
TCTCAAGAGCGAAGCCAGGGCCTACACGCAGGCACTGGAATCCACTGCGGCGCTGATCGATGGCTTTGAGTCGCCCTTTG
GCATGGAACTGTTGGCGACGGTGGACTGGCTGCTGGCCCGCGAAGGAGTCGCGCCCACCGTGCCTGCCTTGCGCAAAGGG
CTGCGCCATTGGCGAGGCGGCCCGGATGCCGGCGCGCGCAAGGATCGTCTCTTTGACGACCGAGCGCTGGGCATTGCGCT
TGAACGCCTGACACAAGCTGCGCCCGCAATTACGTAA
ATGATTACATTCACTCAAGGCAATTTGTTGGAGGCTCGCGCTGAGGCTCTGGTCAACACTGTCAACACCGTTGGGGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGTTTTGACGAGAACTTCCGCCGTTACGCCGCCGCCTGCAAGGCCAAGG
AAGTACGGACTGGTAAGATGTTTGTGACGCCGGTGCACGAGCTGGATGGGCCGCACTGGATCGTCAACTTCCCCACCAAG
CAACACTGGCGCGCACCGTCGCGCATGGAATGGATCATTGAGGGCTTGCAGGATCTGAGGCACTTCTTGATCGAGCAACA
AGTTAAGTCCATCGCCATCCCGCCGCTGGGTGCCGGTAACGGTGGCCTGGAGTGGGCCGACGTGCGCGAGCAGATCGAGC
TGACATTGGGTGATCTGGACATCGACATCCTGGTGTTCGAGCCCACTAAGCAATACCAGAACGTAGCCAAGCGCGCCGGG
GTCGAGAAGCTAACGCCGGCCCGAGCGCTGATTGCCGAGCTGGTGCGGCGGTACTGGGTGTTGGGCATGGAATGCAGCCT
CCTGGAGATTCAGAAGCTGGCGTGGTTTCTGGAGCGTGCGATTGAGCGCTACAACCCGGGTGACAATCCGCTGAACCTGC
AGTTTGCACCGCACAAGTACGGGCCCTATGCCAACCGGCTCGACCACCTACTGAACAATCTGGATGGCAGCTATTTGCAC
TCGGAGAAGCGCATCAGCGACGCCGATCCCCTAGATGTGATCTGGTTTGACGACGAGCGCAAGACTTTTGTGCAGACCTA
TCTCAAGAGCGAAGCCAGGGCCTACACGCAGGCACTGGAATCCACTGCGGCGCTGATCGATGGCTTTGAGTCGCCCTTTG
GCATGGAACTGTTGGCGACGGTGGACTGGCTGCTGGCCCGCGAAGGAGTCGCGCCCACCGTGCCTGCCTTGCGCAAAGGG
CTGCGCCATTGGCGAGGCGGCCCGGATGCCGGCGCGCGCAAGGATCGTCTCTTTGACGACCGAGCGCTGGGCATTGCGCT
TGAACGCCTGACACAAGCTGCGCCCGCAATTACGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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