Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 5164368..5164873 Replicon chromosome
Accession NZ_CP029608
Organism Pseudomonas kribbensis strain 46-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DLD99_RS23520 Protein ID WP_114885380.1
Coordinates 5164619..5164873 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DLD99_RS23515 Protein ID WP_114885378.1
Coordinates 5164368..5164622 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLD99_RS23490 5159659..5160408 - 750 WP_114885368.1 hypothetical protein -
DLD99_RS23495 5160526..5160879 + 354 WP_114885370.1 hypothetical protein -
DLD99_RS23500 5161012..5161755 + 744 WP_114885372.1 hypothetical protein -
DLD99_RS23505 5161828..5163747 + 1920 WP_114885374.1 alkaline phosphatase family protein -
DLD99_RS23510 5163782..5164150 + 369 WP_114885376.1 hypothetical protein -
DLD99_RS23515 5164368..5164622 + 255 WP_114885378.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DLD99_RS23520 5164619..5164873 + 255 WP_114885380.1 Txe/YoeB family addiction module toxin Toxin
DLD99_RS23525 5164882..5166054 - 1173 WP_114885382.1 aspartate aminotransferase family protein -
DLD99_RS23530 5166157..5167062 + 906 WP_114885384.1 LysR family transcriptional regulator -
DLD99_RS23535 5167120..5167524 + 405 Protein_4604 GNAT family N-acetyltransferase -
DLD99_RS23540 5167588..5168103 + 516 WP_114885385.1 hypothetical protein -
DLD99_RS23545 5168122..5168826 - 705 WP_114885387.1 peptide-methionine (S)-S-oxide reductase MsrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9983.53 Da        Isoelectric Point: 8.4955

>T106007 WP_114885380.1 NZ_CP029608:5164619-5164873 [Pseudomonas kribbensis]
MKIEFTPTGWEDYLWFQQNDKAGLKRINLLIKAIQRQPFEGLGKPEPLKHNMSGFWSRRITAEHRLVYAIEDGEVCVITC
RYHY

Download         Length: 255 bp

>T106007 NZ_CP029608:5164619-5164873 [Pseudomonas kribbensis]
ATGAAAATCGAGTTCACGCCAACCGGGTGGGAAGACTACTTATGGTTTCAGCAGAACGATAAGGCCGGTCTCAAACGCAT
CAATCTGTTGATCAAAGCGATCCAACGACAACCCTTCGAAGGACTTGGCAAACCCGAGCCGCTCAAGCACAACATGAGCG
GCTTCTGGTCCCGACGGATAACTGCCGAACATCGTTTGGTCTATGCAATTGAAGACGGTGAAGTCTGCGTCATCACGTGC
AGATATCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9516.97 Da        Isoelectric Point: 7.2027

>AT106007 WP_114885378.1 NZ_CP029608:5164368-5164622 [Pseudomonas kribbensis]
MHTINYTTARAHLAETMDRVNEDRAPLLITRQKGEPVVMMSLAEYNAMEETAYLLRSPANAERLIKSIGEMRAGKAKARQ
LIEE

Download         Length: 255 bp

>AT106007 NZ_CP029608:5164368-5164622 [Pseudomonas kribbensis]
ATGCACACCATCAACTACACCACGGCCCGGGCTCACCTGGCGGAAACCATGGACCGCGTGAACGAAGATCGCGCCCCGCT
GCTGATCACCCGCCAAAAAGGTGAACCTGTTGTCATGATGTCTCTGGCTGAATACAACGCGATGGAAGAAACGGCATATC
TGCTGCGTTCTCCAGCCAACGCAGAGCGCTTGATCAAATCGATTGGCGAAATGCGTGCAGGAAAAGCCAAAGCCAGGCAA
CTGATCGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References