Detailed information of TA system TA106006

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3524892..3525360
• Replicon: chromosome
• Accession: NZ_CP029608
• Organism: Pseudomonas kribbensis strain 46-2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DLD99_RS16030
• Protein ID: WP_114883547.1
• Coordinates: 3525076..3525360 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q3KBE7
• Locus tag: DLD99_RS16025
• Protein ID: WP_011334551.1
• Coordinates: 3524892..3525086 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DLD99_RS16005	3520520..3521488	-	969	WP_114883539.1	Gfo/Idh/MocA family oxidoreductase	-
DLD99_RS16010	3521498..3522385	-	888	WP_114883541.1	Dyp-type peroxidase	-
DLD99_RS16015	3522443..3523477	-	1035	WP_114883543.1	AraC family transcriptional regulator	-
DLD99_RS16020	3523689..3524636	+	948	WP_114883545.1	transporter	-
DLD99_RS16025	3524892..3525086	+	195	WP_011334551.1	hypothetical protein	Antitoxin
DLD99_RS16030	3525076..3525360	+	285	WP_114883547.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10697.11 Da
• Isoelectric Point: 9.9115

>T106006 WP_114883547.1 NZ_CP029608:3525076-3525360 [Pseudomonas kribbensis]
MPLEWSNQALDDLADIIDYVEQYNSNASTALQHKVGAATQRLSSIPYGYRSGRVPGTREMVVNPNYLLVYRVNGRIKILT
LVHTRRQYPRTSST

Nucleotide

• Length: 285 bp

>T106006 NZ_CP029608:3525076-3525360 [Pseudomonas kribbensis]
CTGCCGCTTGAATGGAGCAATCAAGCTCTGGACGATCTGGCTGACATTATCGATTACGTTGAACAATACAACTCAAACGC
TTCAACGGCTCTGCAACACAAGGTTGGTGCAGCAACGCAAAGGCTTTCATCAATCCCCTATGGTTACCGGTCCGGTCGAG
TGCCAGGCACTCGGGAAATGGTGGTCAATCCAAACTATCTGCTGGTCTATCGAGTGAACGGCCGCATCAAAATACTGACG
TTAGTCCACACCCGACGACAATACCCACGAACCTCATCAACCTAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7590.45 Da
• Isoelectric Point: 4.8177

>AT106006 WP_011334551.1 NZ_CP029608:3524892-3525086 [Pseudomonas kribbensis]
MSILHSPFYSDFESEEEAESYDRWFRAKVQAVLDDPRPGIPHEEAMVRLDQLLEERRKNRRAAA

Nucleotide

• Length: 195 bp

>AT106006 NZ_CP029608:3524892-3525086 [Pseudomonas kribbensis]
ATGAGCATATTGCATTCCCCGTTTTACTCTGACTTCGAATCCGAAGAAGAGGCAGAGAGCTACGATCGCTGGTTTCGTGC
CAAGGTGCAGGCTGTACTGGATGATCCTCGCCCGGGTATTCCCCATGAGGAAGCCATGGTGCGGCTCGACCAACTATTAG
AAGAGAGACGCAAGAATCGACGCGCTGCCGCTTGA

Structures

Antitoxin

• AlphaFold DB: A0A345RRJ8