Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/Acetyltransf_9(toxin)
Location 2761759..2763469 Replicon chromosome
Accession NZ_CP029608
Organism Pseudomonas kribbensis strain 46-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DLD99_RS12575 Protein ID WP_114882450.1
Coordinates 2761759..2762826 (-) Length 356 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DLD99_RS12580 Protein ID WP_114882451.1
Coordinates 2762912..2763469 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLD99_RS12550 2757227..2757862 - 636 WP_114882446.1 DUF1842 domain-containing protein -
DLD99_RS12555 2757896..2758081 - 186 WP_114886659.1 DUF1843 domain-containing protein -
DLD99_RS12560 2758641..2759558 + 918 WP_114882447.1 LysR family transcriptional regulator -
DLD99_RS12565 2759597..2760205 - 609 WP_114882448.1 3-isopropylmalate dehydratase small subunit -
DLD99_RS12570 2760209..2761630 - 1422 WP_114882449.1 3-isopropylmalate dehydratase large subunit -
DLD99_RS12575 2761759..2762826 - 1068 WP_114882450.1 GNAT family N-acetyltransferase Toxin
DLD99_RS12580 2762912..2763469 - 558 WP_114882451.1 helix-turn-helix domain-containing protein Antitoxin
DLD99_RS12585 2763543..2763950 - 408 WP_114882453.1 RidA family protein -
DLD99_RS12590 2764085..2765026 + 942 WP_114882455.1 LysR family transcriptional regulator -
DLD99_RS12595 2764989..2765849 - 861 WP_114882457.1 LysR family transcriptional regulator -
DLD99_RS12600 2765987..2767039 + 1053 WP_114882459.1 agmatine deiminase family protein -
DLD99_RS12605 2767043..2767951 + 909 WP_114882461.1 N-carbamoylputrescine amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-172)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-53)


Sequences

Toxin        


Download         Length: 356 a.a.        Molecular weight: 38996.92 Da        Isoelectric Point: 4.7514

>T106005 WP_114882450.1 NZ_CP029608:c2762826-2761759 [Pseudomonas kribbensis]
MNLEKIKGRLEFLREAERLKDVLRSAHTSSGRSESTAEHSWRLCLMAIVFADDLAGLDVLKVLKMCVIHDLGEAINGDIP
AVDQAGFPDKGEQERNDLLLLTRSLDDALRNEILALWDDYENAGSPEAKAVKALDKLETLLQHTQGQNPPDFDYGFNLAY
GKQYTNADPLFETLRTLIDRDTRERMNTNITVRNERPEDIDAIARITEAAFQHEEHSSHTEQFIVNALRHAGQLSVSLVA
VENDTVVGHVAISPVTISSGAQGWYGLGPISVCPTRQQQGIGSALMRASLTELQRIGGVGCVVLGDPGYYGRFGFKAHAG
LELPGIPAEYFQALAFGGELPVGVVKYHEAFEATE

Download         Length: 1068 bp

>T106005 NZ_CP029608:c2762826-2761759 [Pseudomonas kribbensis]
ATGAACCTCGAAAAAATCAAGGGACGCCTCGAATTCCTGCGTGAAGCAGAACGGCTCAAGGACGTCCTCAGAAGCGCACA
CACTTCCTCCGGGCGCAGCGAAAGCACCGCCGAACACAGCTGGCGCCTGTGCCTGATGGCGATCGTGTTCGCCGACGACC
TGGCCGGGCTCGACGTGCTGAAAGTCCTGAAGATGTGCGTCATCCACGACCTCGGAGAGGCCATCAACGGTGACATTCCG
GCGGTCGATCAAGCCGGCTTTCCCGACAAGGGCGAACAGGAACGCAACGACTTGCTGCTGCTCACCCGGTCTCTGGACGA
CGCGCTGAGAAACGAAATCCTTGCGCTCTGGGACGACTACGAAAACGCCGGCTCTCCAGAAGCCAAGGCCGTGAAGGCAC
TGGACAAGCTGGAAACACTTTTACAACACACTCAAGGACAGAATCCGCCAGACTTCGACTATGGCTTCAACCTGGCCTAC
GGCAAGCAATACACCAACGCCGATCCGCTGTTCGAAACCCTTCGGACCCTGATCGACCGGGATACCCGAGAACGCATGAA
TACAAACATCACCGTCCGCAACGAACGCCCCGAAGACATCGACGCCATCGCCCGAATCACCGAGGCCGCGTTCCAGCACG
AAGAACACTCCAGCCACACCGAACAATTCATCGTCAACGCCTTGCGCCACGCCGGTCAGCTCAGCGTTTCGCTGGTGGCA
GTGGAAAACGACACGGTGGTCGGCCATGTCGCCATTTCCCCCGTAACGATTTCCTCCGGCGCTCAAGGCTGGTATGGCCT
GGGCCCGATCTCCGTGTGCCCGACCCGCCAGCAGCAAGGCATCGGCTCGGCGCTGATGAGAGCCTCACTGACGGAGTTGC
AGCGCATTGGCGGCGTTGGCTGCGTGGTACTTGGCGATCCGGGCTATTACGGTCGTTTCGGCTTCAAGGCCCATGCGGGT
CTGGAGTTGCCGGGGATTCCGGCGGAGTACTTTCAGGCGTTGGCGTTTGGTGGGGAGTTGCCGGTGGGCGTGGTGAAATA
TCACGAGGCGTTCGAGGCTACCGAGTAG

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20473.39 Da        Isoelectric Point: 7.4059

>AT106005 WP_114882451.1 NZ_CP029608:c2763469-2762912 [Pseudomonas kribbensis]
MPDTLLQPSLPGIALRRWRVLHRVKQSHAAELFKVTQSTISRWESGVQAMDPEAHRQLETLLSARLDSAADQALARLVTE
SARPVHLVCDLTHRLLACSPARAAQFASPLSDLLGQSLWRFATAEIQHKESLLDDTGWREVQAPPALEFLTGSNDSARVP
IQPSLCRWTRIALSDGTAARLVETL

Download         Length: 558 bp

>AT106005 NZ_CP029608:c2763469-2762912 [Pseudomonas kribbensis]
ATGCCCGACACCTTGCTCCAGCCCAGCCTGCCCGGCATCGCCCTGCGCCGCTGGCGGGTGCTGCACCGCGTCAAGCAAAG
TCATGCCGCCGAGTTGTTCAAGGTCACTCAATCGACGATTTCCCGCTGGGAAAGCGGCGTGCAGGCGATGGATCCGGAGG
CGCATCGACAACTCGAGACTTTGCTCTCGGCGCGACTCGACAGCGCCGCCGATCAAGCCCTCGCACGGCTGGTGACGGAA
AGTGCGCGCCCGGTTCACCTGGTCTGCGACCTGACCCATCGCCTGCTGGCCTGCTCACCTGCCCGCGCCGCGCAGTTCGC
CAGCCCGCTGAGCGATCTGCTGGGGCAATCGCTGTGGCGGTTTGCGACAGCGGAAATCCAGCACAAGGAATCCTTGCTGG
ATGACACCGGCTGGCGGGAAGTCCAGGCGCCGCCGGCTCTGGAATTCCTGACGGGCAGCAATGACTCCGCCCGTGTGCCG
ATCCAGCCGAGTCTCTGCCGCTGGACGCGGATCGCCCTCTCCGACGGCACCGCCGCACGGTTGGTGGAAACGCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References