Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pezAT/zeta-ParD |
| Location | 4938569..4939524 | Replicon | chromosome |
| Accession | NZ_CP029604 | ||
| Organism | Gordonia terrae strain NRRL B-16283 | ||
Toxin (Protein)
| Gene name | pezT | Uniprot ID | A0A4V0B4G9 |
| Locus tag | DLJ61_RS22075 | Protein ID | WP_004022298.1 |
| Coordinates | 4938569..4939144 (-) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | pezA | Uniprot ID | A0A4V0B2G5 |
| Locus tag | DLJ61_RS22080 | Protein ID | WP_004022299.1 |
| Coordinates | 4939141..4939524 (-) | Length | 128 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DLJ61_RS22045 | 4934031..4935038 | + | 1008 | WP_004022292.1 | LacI family transcriptional regulator | - |
| DLJ61_RS22050 | 4935061..4935741 | - | 681 | WP_033204814.1 | hypothetical protein | - |
| DLJ61_RS22055 | 4935840..4936154 | - | 315 | WP_004022294.1 | DUF2470 domain-containing protein | - |
| DLJ61_RS22060 | 4936147..4936878 | - | 732 | WP_004022295.1 | tyrosine-protein phosphatase | - |
| DLJ61_RS22065 | 4936971..4937603 | + | 633 | WP_004022296.1 | flavin reductase family protein | - |
| DLJ61_RS22070 | 4937625..4938572 | - | 948 | WP_004022297.1 | ribokinase | - |
| DLJ61_RS22075 | 4938569..4939144 | - | 576 | WP_004022298.1 | zeta toxin family protein | Toxin |
| DLJ61_RS22080 | 4939141..4939524 | - | 384 | WP_004022299.1 | hypothetical protein | Antitoxin |
| DLJ61_RS22085 | 4939648..4940196 | - | 549 | WP_004022300.1 | peptide-methionine (S)-S-oxide reductase MsrA | - |
| DLJ61_RS22090 | 4940193..4940675 | - | 483 | WP_004022301.1 | peptide-methionine (R)-S-oxide reductase MsrB | - |
| DLJ61_RS22095 | 4940835..4942058 | - | 1224 | WP_051987126.1 | acyl-CoA dehydrogenase family protein | - |
| DLJ61_RS22100 | 4942137..4943219 | - | 1083 | WP_004022303.1 | VOC family protein | - |
| DLJ61_RS22105 | 4943467..4944360 | + | 894 | WP_004022304.1 | acetaldehyde dehydrogenase (acetylating) | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21075.04 Da Isoelectric Point: 8.1649
>T105994 WP_004022298.1 NZ_CP029604:c4939144-4938569 [Gordonia terrae]
VTPRLDLVVGCNGAGKSTLVEHHLQPLVRTPFVNADLIARQQWPDAAEAHSYDAARLAAATRDHLIEAGASFIAETVFSH
PSKLELIDRAHTAGYRVALHVVMIPEDLAVHRVRLRVDSGGHAVPEVKIRERFRRLWPLVRTAILRSDQATVYANERATT
RIVARYVDGMVAGVPDWPDWTPGALTGSEAR
VTPRLDLVVGCNGAGKSTLVEHHLQPLVRTPFVNADLIARQQWPDAAEAHSYDAARLAAATRDHLIEAGASFIAETVFSH
PSKLELIDRAHTAGYRVALHVVMIPEDLAVHRVRLRVDSGGHAVPEVKIRERFRRLWPLVRTAILRSDQATVYANERATT
RIVARYVDGMVAGVPDWPDWTPGALTGSEAR
Download Length: 576 bp
>T105994 NZ_CP029604:c4939144-4938569 [Gordonia terrae]
GTGACACCGAGGCTCGACCTGGTCGTCGGATGCAACGGCGCGGGAAAGTCGACGCTGGTCGAGCATCATCTACAGCCGTT
GGTGCGCACACCCTTCGTGAACGCCGACCTGATCGCCCGGCAGCAGTGGCCCGACGCCGCGGAAGCCCACTCCTACGACG
CGGCCCGGTTGGCCGCGGCCACCCGCGACCACCTCATCGAGGCCGGTGCCTCGTTCATCGCCGAGACGGTCTTCTCGCAT
CCGTCGAAACTGGAACTCATCGACCGTGCGCACACCGCCGGATACCGGGTCGCTCTCCATGTCGTGATGATCCCCGAAGA
TCTCGCCGTGCATCGGGTGCGGCTACGCGTCGACAGTGGGGGGCATGCGGTCCCGGAGGTCAAGATCCGCGAGCGGTTCC
GACGCCTGTGGCCGCTCGTCCGCACGGCGATCCTGCGGAGTGACCAGGCAACCGTGTACGCCAACGAGCGAGCGACCACG
CGCATCGTCGCGAGGTACGTCGACGGTATGGTCGCGGGCGTGCCCGACTGGCCCGACTGGACGCCGGGGGCGCTCACGGG
TTCGGAGGCACGATGA
GTGACACCGAGGCTCGACCTGGTCGTCGGATGCAACGGCGCGGGAAAGTCGACGCTGGTCGAGCATCATCTACAGCCGTT
GGTGCGCACACCCTTCGTGAACGCCGACCTGATCGCCCGGCAGCAGTGGCCCGACGCCGCGGAAGCCCACTCCTACGACG
CGGCCCGGTTGGCCGCGGCCACCCGCGACCACCTCATCGAGGCCGGTGCCTCGTTCATCGCCGAGACGGTCTTCTCGCAT
CCGTCGAAACTGGAACTCATCGACCGTGCGCACACCGCCGGATACCGGGTCGCTCTCCATGTCGTGATGATCCCCGAAGA
TCTCGCCGTGCATCGGGTGCGGCTACGCGTCGACAGTGGGGGGCATGCGGTCCCGGAGGTCAAGATCCGCGAGCGGTTCC
GACGCCTGTGGCCGCTCGTCCGCACGGCGATCCTGCGGAGTGACCAGGCAACCGTGTACGCCAACGAGCGAGCGACCACG
CGCATCGTCGCGAGGTACGTCGACGGTATGGTCGCGGGCGTGCCCGACTGGCCCGACTGGACGCCGGGGGCGCTCACGGG
TTCGGAGGCACGATGA
Antitoxin
Download Length: 128 a.a. Molecular weight: 13813.28 Da Isoelectric Point: 5.2682
>AT105994 WP_004022299.1 NZ_CP029604:c4939524-4939141 [Gordonia terrae]
MSTGTDKVTRLSAALVTDAAREGAREQRSARQQLEHWARLGRSVSQRTTASRRRVEAALAGDLPAETLTAEEAVVYDAEI
DAHIEARLATDDHVVRRASEGFASVVVDDAGRLVELRPDGTSVVFDR
MSTGTDKVTRLSAALVTDAAREGAREQRSARQQLEHWARLGRSVSQRTTASRRRVEAALAGDLPAETLTAEEAVVYDAEI
DAHIEARLATDDHVVRRASEGFASVVVDDAGRLVELRPDGTSVVFDR
Download Length: 384 bp
>AT105994 NZ_CP029604:c4939524-4939141 [Gordonia terrae]
ATGAGCACCGGTACGGACAAGGTGACCCGATTGTCTGCTGCACTGGTGACCGATGCCGCCCGGGAGGGCGCGCGCGAGCA
GCGATCGGCGCGGCAGCAACTCGAACACTGGGCACGTCTCGGCCGCAGCGTCTCACAGCGCACCACCGCGTCGCGTCGGC
GGGTCGAGGCCGCGTTGGCCGGCGACCTACCGGCAGAGACGTTGACCGCAGAGGAAGCCGTCGTCTACGACGCCGAGATC
GACGCGCACATCGAGGCGCGGCTGGCCACCGACGACCATGTCGTCCGACGCGCCTCGGAGGGGTTCGCCTCGGTCGTCGT
CGATGACGCCGGACGGCTCGTCGAACTCCGGCCCGACGGGACGAGCGTCGTCTTCGACCGGTGA
ATGAGCACCGGTACGGACAAGGTGACCCGATTGTCTGCTGCACTGGTGACCGATGCCGCCCGGGAGGGCGCGCGCGAGCA
GCGATCGGCGCGGCAGCAACTCGAACACTGGGCACGTCTCGGCCGCAGCGTCTCACAGCGCACCACCGCGTCGCGTCGGC
GGGTCGAGGCCGCGTTGGCCGGCGACCTACCGGCAGAGACGTTGACCGCAGAGGAAGCCGTCGTCTACGACGCCGAGATC
GACGCGCACATCGAGGCGCGGCTGGCCACCGACGACCATGTCGTCCGACGCGCCTCGGAGGGGTTCGCCTCGGTCGTCGT
CGATGACGCCGGACGGCTCGTCGAACTCCGGCCCGACGGGACGAGCGTCGTCTTCGACCGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A4V0B4G9 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A4V0B2G5 |