Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 55168..55693 Replicon plasmid pDA34827-94
Accession NZ_CP029594
Organism Salmonella enterica strain DA34827

Toxin (Protein)


Gene name ccdB Uniprot ID I3W3D5
Locus tag DLJ69_RS25895 Protein ID WP_001159863.1
Coordinates 55168..55473 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID M7S5D0
Locus tag DLJ69_RS25900 Protein ID WP_000813641.1
Coordinates 55475..55693 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLJ69_RS25855 50547..51107 - 561 WP_000900095.1 inverse autotransporter beta domain-containing protein -
DLJ69_RS26235 51263..51550 + 288 WP_071530243.1 hypothetical protein -
DLJ69_RS25860 51827..52312 - 486 WP_000905606.1 membrane protein -
DLJ69_RS25865 52306..52815 - 510 WP_001541544.1 CaiF/GrlA family transcriptional regulator -
DLJ69_RS25875 52819..53532 - 714 Protein_69 EAL domain-containing protein -
DLJ69_RS25880 53541..54323 - 783 WP_000082169.1 site-specific integrase -
DLJ69_RS25885 54358..54879 - 522 WP_000198608.1 hypothetical protein -
DLJ69_RS25890 54876..55166 - 291 WP_001266176.1 hypothetical protein -
DLJ69_RS25895 55168..55473 - 306 WP_001159863.1 type II toxin-antitoxin system toxin CcdB Toxin
DLJ69_RS25900 55475..55693 - 219 WP_000813641.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
DLJ69_RS25905 56369..56890 + 522 WP_010999942.1 hypothetical protein -
DLJ69_RS25915 57374..57670 + 297 WP_001687482.1 hypothetical protein -
DLJ69_RS25920 58164..59153 + 990 WP_001527061.1 RepB family plasmid replication initiator protein -
DLJ69_RS25925 59412..59748 - 337 Protein_78 site-specific integrase -
DLJ69_RS25930 60025..60406 - 382 Protein_79 NirD/YgiW/YdeI family stress tolerance protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..94034 94034


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 15030.03 Da        Isoelectric Point: 5.5500

>T105971 WP_001159863.1 NZ_CP029594:c55473-55168 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF

Download         Length: 306 bp

>T105971 NZ_CP029594:c55473-55168 [Salmonella enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 10761.91 Da        Isoelectric Point: 5.5500

>AT105971 WP_000813641.1 NZ_CP029594:c55693-55475 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 219 bp

>AT105971 NZ_CP029594:c55693-55475 [Salmonella enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I3W3D5

Antitoxin

Source ID Structure
AlphaFold DB A0A656ICA6

References