Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3475698..3475843 Replicon chromosome
Accession NZ_CP029590
Organism Klebsiella pneumoniae strain DA33144

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3475734..3475836 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3475698..3475843 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLJ67_RS17360 3470828..3472888 + 2061 WP_004151449.1 oligopeptidase B -
DLJ67_RS17365 3472892..3473551 - 660 WP_002911407.1 exodeoxyribonuclease X -
DLJ67_RS17370 3473630..3473860 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DLJ67_RS17375 3473973..3474347 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DLJ67_RS17380 3474351..3475220 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
DLJ67_RS17385 3475237..3475575 + 339 WP_009307539.1 YebY family protein -
- 3475698..3475843 - 146 - - Antitoxin
- 3475734..3475836 + 103 - - Toxin
DLJ67_RS28580 3476212..3476355 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DLJ67_RS17395 3476460..3477428 - 969 WP_004151446.1 VirK/YbjX family protein -
DLJ67_RS17400 3477585..3478238 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
DLJ67_RS17405 3478235..3478426 - 192 WP_002911395.1 YebW family protein -
DLJ67_RS17410 3478524..3478763 - 240 WP_002911393.1 YebV family protein -
DLJ67_RS17415 3478879..3480312 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T105959 NZ_CP029590:3475734-3475836 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT105959 NZ_CP029590:c3475843-3475698 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References