Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3975261..3975763 Replicon chromosome
Accession NZ_CP029488
Organism Salinisphaera sp. LB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SALB1_RS17825 Protein ID WP_109995073.1
Coordinates 3975261..3975515 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SALB1_RS17830 Protein ID WP_109995074.1
Coordinates 3975512..3975763 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SALB1_RS17805 3970884..3971282 - 399 WP_147420775.1 hypothetical protein -
SALB1_RS17810 3971421..3972584 + 1164 WP_109995072.1 acetylornithine deacetylase -
SALB1_RS17815 3972684..3973991 + 1308 WP_109995522.1 amino-acid N-acetyltransferase -
SALB1_RS17820 3974018..3974746 + 729 WP_109995523.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
SALB1_RS17825 3975261..3975515 - 255 WP_109995073.1 Txe/YoeB family addiction module toxin Toxin
SALB1_RS17830 3975512..3975763 - 252 WP_109995074.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SALB1_RS18910 3975962..3976276 - 315 WP_145961379.1 hypothetical protein -
SALB1_RS17835 3976489..3977451 + 963 WP_109995075.1 glutathione synthase -
SALB1_RS17840 3977560..3978114 + 555 WP_109995076.1 YqgE/AlgH family protein -
SALB1_RS17845 3978107..3978550 + 444 WP_109995077.1 Holliday junction resolvase RuvX -
SALB1_RS17850 3978645..3979145 + 501 WP_109995078.1 bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR -
SALB1_RS17855 3979316..3980293 + 978 WP_109995079.1 aspartate carbamoyltransferase catalytic subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10146.66 Da        Isoelectric Point: 9.8548

>T105718 WP_109995073.1 NZ_CP029488:c3975515-3975261 [Salinisphaera sp. LB1]
MKLTFSEHAWEDYLYWQKTEKKTLRRINQLIKEIQRTPFEGIGKPEPLKHGLSGYGSRRINDEHRLVYKVTEDALLIAQL
RYHY

Download         Length: 255 bp

>T105718 NZ_CP029488:c3975515-3975261 [Salinisphaera sp. LB1]
ATGAAACTCACCTTTTCCGAGCATGCCTGGGAAGACTACCTCTACTGGCAGAAAACGGAAAAAAAGACCCTGCGCCGCAT
CAATCAGCTCATCAAAGAGATTCAGCGAACGCCGTTCGAGGGTATCGGCAAACCGGAGCCGCTCAAGCACGGCCTGTCCG
GATACGGGTCTCGACGCATCAATGACGAACATCGGCTCGTGTACAAGGTAACCGAGGACGCACTTCTTATTGCGCAATTG
CGATATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9264.50 Da        Isoelectric Point: 4.5037

>AT105718 WP_109995074.1 NZ_CP029488:c3975763-3975512 [Salinisphaera sp. LB1]
MDAISYTAARTHLAKTMEQVCDDHAPVIITRSKAASVVMMSLEDYEALQETAYLLRAPRNARRLLESVAELEQGGGEERE
LLE

Download         Length: 252 bp

>AT105718 NZ_CP029488:c3975763-3975512 [Salinisphaera sp. LB1]
ATGGACGCCATCAGCTACACGGCCGCCAGAACCCACCTGGCAAAAACAATGGAACAGGTCTGTGACGACCACGCCCCCGT
TATCATCACCAGAAGCAAGGCCGCTTCGGTGGTGATGATGTCCCTGGAAGACTATGAAGCCCTTCAGGAGACTGCATACC
TGTTGCGTGCGCCCAGGAACGCGCGCCGTCTGCTCGAATCGGTTGCCGAGCTGGAACAAGGGGGCGGCGAGGAGAGGGAG
CTTCTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References