Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 9879..11358 Replicon chromosome
Accession NZ_CP029488
Organism Salinisphaera sp. LB1

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag SALB1_RS00050 Protein ID WP_109991998.1
Coordinates 9879..10748 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag SALB1_RS00055 Protein ID WP_109991999.1
Coordinates 10741..11358 (-) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SALB1_RS00035 5262..5528 - 267 WP_158590551.1 hypothetical protein -
SALB1_RS00040 5603..6826 - 1224 Protein_5 IS3 family transposase -
SALB1_RS00045 6874..9822 - 2949 WP_109991997.1 ATP-binding protein -
SALB1_RS00050 9879..10748 - 870 WP_109991998.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
SALB1_RS00055 10741..11358 - 618 WP_109991999.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
SALB1_RS00060 11535..11951 - 417 Protein_9 ATP-binding domain-containing protein -
SALB1_RS00065 12133..13287 + 1155 WP_109995192.1 ISL3 family transposase -
SALB1_RS00070 13312..13623 - 312 Protein_11 helicase -
SALB1_RS00075 13769..14196 - 428 Protein_12 transposase -
SALB1_RS00080 14465..14968 + 504 WP_109992000.1 OsmC family peroxiredoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 448..42533 42085


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-265)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-56)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32434.11 Da        Isoelectric Point: 4.8894

>T105715 WP_109991998.1 NZ_CP029488:c10748-9879 [Salinisphaera sp. LB1]
MAKEIKNIGASVRARLLKLSKANGQSFDLVLTRFALERLLFRLSQSPYADRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPSEEAMLATFRGILAQYAEDGVVFDSETLRVDRIREELDYGGLRLRGIASVGGARVNLTIDIGFGDALEPGAEVVDYPV
MLDLPAPRLRAYARETVIAEKFQAMVALGRANSRMKDFYDIWILSRSFDFDNDKLAQAIAATFVRRKTAIPTEPPDALSP
AFARDEQKQRQWRAFVEDVAIDPGPLAQVLEEISGFLMPRANRENELDQ

Download         Length: 870 bp

>T105715 NZ_CP029488:c10748-9879 [Salinisphaera sp. LB1]
ATGGCTAAGGAGATCAAGAATATCGGCGCCTCCGTGCGCGCCCGGCTTCTCAAGCTCTCCAAGGCGAACGGACAGAGTTT
CGATCTTGTGCTCACGCGCTTCGCGTTGGAGCGTCTTCTATTCCGGCTTAGCCAATCACCCTATGCGGATCGCTTCGTGC
TGAAAGGTGCCATGCTGATGATGAGCTGGTTCGACGATCCGCACCGCGGAACGCGCGATCTCGATCTATTGGGTTTCGGC
GATCCAAGTGAGGAGGCGATGCTGGCGACGTTCCGGGGCATCCTCGCTCAGTATGCCGAAGACGGTGTCGTCTTCGATTC
TGAAACCTTGCGTGTCGACCGCATTCGCGAAGAGCTCGACTATGGCGGTCTCCGGCTACGCGGCATCGCCTCAGTCGGAG
GCGCCCGGGTCAACCTGACGATCGATATCGGTTTCGGGGATGCGCTGGAGCCCGGAGCTGAAGTCGTCGACTATCCGGTC
ATGCTGGATCTCCCCGCGCCGAGGCTGCGCGCCTATGCGCGAGAGACGGTCATTGCCGAGAAGTTCCAGGCGATGGTGGC
GCTGGGGCGTGCGAACAGCCGGATGAAGGATTTTTATGACATCTGGATACTCAGCCGGTCGTTTGATTTCGATAATGACA
AGCTTGCACAAGCGATCGCAGCAACGTTCGTGCGGCGCAAGACGGCGATTCCGACCGAGCCGCCCGATGCGCTCTCGCCG
GCATTTGCAAGAGATGAACAGAAGCAGCGACAGTGGCGTGCTTTCGTCGAGGATGTTGCAATTGATCCCGGACCTCTCGC
ACAAGTTCTTGAGGAGATTTCTGGGTTTTTAATGCCGCGGGCCAATCGGGAAAACGAACTGGATCAATAG

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22403.92 Da        Isoelectric Point: 9.1449

>AT105715 WP_109991999.1 NZ_CP029488:c11358-10741 [Salinisphaera sp. LB1]
MTQMRSQRDIARDLLATHGILRLVELREAGVTAATVSRMERDGEVIRLARGLYQLPDAELDTNHSLAEAAKRFPKGVICL
VSALAFHGITDQLPKKVWMAIGRNDWTPKPSDMPIRVLRFSDDLLVESVETHVIEGVSVKVFGVAKTVADCFRHRGKIGL
AVALEGLQEALRQRKATPAEVARAADTGGVGTVIRPYLEALTTNG

Download         Length: 618 bp

>AT105715 NZ_CP029488:c11358-10741 [Salinisphaera sp. LB1]
ATGACCCAGATGCGATCCCAGCGCGATATAGCCCGCGATCTCCTCGCGACGCATGGGATTCTGCGCCTTGTGGAACTCCG
GGAAGCGGGAGTGACCGCCGCAACGGTCAGTCGTATGGAGAGGGATGGCGAGGTGATCCGCCTGGCGCGCGGACTCTACC
AGCTTCCCGATGCCGAGCTGGATACAAACCATAGCCTTGCCGAAGCGGCCAAGCGTTTTCCCAAGGGCGTGATCTGCCTC
GTATCGGCACTCGCTTTTCATGGAATCACGGATCAGCTACCGAAAAAGGTGTGGATGGCAATCGGCCGGAACGACTGGAC
GCCGAAGCCAAGCGATATGCCGATTCGTGTGCTGCGTTTCTCGGATGATCTGCTCGTCGAAAGCGTCGAGACGCATGTGA
TCGAGGGCGTGTCGGTGAAGGTGTTCGGCGTGGCGAAGACCGTCGCCGACTGCTTCCGGCATCGCGGCAAGATAGGTCTC
GCCGTCGCGCTCGAAGGGCTGCAGGAAGCTCTGCGTCAACGCAAGGCGACGCCGGCCGAGGTCGCCAGGGCGGCGGATAC
TGGCGGGGTCGGCACCGTGATCCGCCCCTACCTGGAGGCGCTGACCACCAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References