105712

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 894821..895416 Replicon chromosome
Accession NZ_CP029482
Organism Pseudomonas sp. 31-12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DJ564_RS04105 Protein ID WP_109627767.1
Coordinates 895108..895416 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DJ564_RS04100 Protein ID WP_109627766.1
Coordinates 894821..895111 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DJ564_RS04080 890984..893101 - 2118 WP_109627762.1 TonB-dependent copper receptor -
DJ564_RS04085 893326..893775 - 450 WP_109627763.1 DUF2946 domain-containing protein -
DJ564_RS04090 893796..894275 - 480 WP_109627764.1 copper chaperone PCu(A)C -
DJ564_RS04095 894324..894722 - 399 WP_109627765.1 DUF2946 domain-containing protein -
DJ564_RS04100 894821..895111 - 291 WP_109627766.1 putative addiction module antidote protein Antitoxin
DJ564_RS04105 895108..895416 - 309 WP_109627767.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DJ564_RS04110 895608..896336 - 729 WP_109627768.1 cobalt-precorrin-6A reductase -
DJ564_RS04115 896333..897430 - 1098 WP_109627769.1 cobalt-precorrin-5B (C(1))-methyltransferase -
DJ564_RS04120 897423..898634 - 1212 WP_109627770.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
DJ564_RS04125 898778..900085 + 1308 WP_109627771.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-94)

Antitoxin

Uncharacterized protein HI1420

(3-95)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11582.18 Da        Isoelectric Point: 8.8773

>T105712 WP_109627767.1 NZ_CP029482:c895416-895108 [Pseudomonas sp. 31-12]
MIDFERSRAFGDWLDSLRDVIGKARIIAKLRAAEHENFGDCEPVGGTVYEMRVHYGPGYRIYFTRRGEVVYLLLMGGDKS
TQKRDIKRAIQLAQNIGNGESS

Download         Length: 309 bp

>T105712 NZ_CP029482:c895416-895108 [Pseudomonas sp. 31-12]
ATGATCGACTTTGAACGATCCCGAGCATTTGGTGATTGGCTTGATTCACTGAGAGACGTCATTGGCAAAGCTCGGATCAT
CGCGAAGCTTCGAGCAGCCGAACATGAGAATTTCGGAGATTGCGAACCCGTAGGCGGCACTGTTTATGAAATGCGCGTGC
ATTACGGTCCCGGTTACAGGATCTATTTCACCCGACGAGGTGAAGTGGTTTATCTGCTGCTGATGGGCGGTGACAAGTCG
ACACAAAAACGAGATATCAAACGCGCCATTCAACTAGCGCAAAACATCGGTAATGGGGAGTCATCATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10370.85 Da        Isoelectric Point: 4.5858

>AT105712 WP_109627766.1 NZ_CP029482:c895111-894821 [Pseudomonas sp. 31-12]
MTEQFTRFDAAEFLKTPEEMAAYLDACFDEDAGDGVLIRAALNDIARAQGMTQVARDAGLGRESLYKALGSTGNPEFATI
MKVMKALGLRLHATAL

Download         Length: 291 bp

>AT105712 NZ_CP029482:c895111-894821 [Pseudomonas sp. 31-12]
ATGACCGAACAATTCACCCGTTTCGACGCTGCCGAATTTCTCAAAACACCTGAGGAAATGGCCGCTTATCTGGATGCATG
CTTTGACGAAGATGCAGGCGATGGAGTGCTCATACGTGCCGCACTCAACGACATTGCCCGCGCACAGGGTATGACCCAGG
TTGCCCGTGACGCAGGCCTGGGTCGTGAAAGTTTGTACAAAGCATTGGGAAGCACTGGCAATCCGGAATTCGCGACTATC
ATGAAGGTTATGAAAGCCTTGGGCCTGCGCTTGCATGCCACGGCTCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References