Detailed information of TA system TA105709

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 399986..400502
• Replicon: chromosome
• Accession: NZ_CP029482
• Organism: Pseudomonas sp. 31-12

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DJ564_RS01825
• Protein ID: WP_109627206.1
• Coordinates: 400221..400502 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: DJ564_RS01820
• Protein ID: WP_109627204.1
• Coordinates: 399986..400231 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DJ564_RS01795	396796..397179	-	384	WP_109627197.1	hypothetical protein	-
DJ564_RS01800	397506..398264	-	759	WP_109627199.1	slipin family protein	-
DJ564_RS01805	398267..398797	-	531	WP_109635916.1	serine protease	-
DJ564_RS01810	398996..399457	+	462	WP_109627200.1	YbaK/EbsC family protein	-
DJ564_RS01815	399595..399840	+	246	WP_109627202.1	DUF2789 domain-containing protein	-
DJ564_RS01820	399986..400231	+	246	WP_109627204.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
DJ564_RS01825	400221..400502	+	282	WP_109627206.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DJ564_RS01830	400519..400701	-	183	WP_109627208.1	hypothetical protein	-
DJ564_RS01835	400894..401322	+	429	WP_109627210.1	winged helix DNA-binding protein	-
DJ564_RS01840	401319..403391	+	2073	WP_109627212.1	FUSC family protein	-
DJ564_RS01845	403388..403597	+	210	WP_008148151.1	DUF1656 domain-containing protein	-
DJ564_RS01850	403594..404481	+	888	WP_109627214.1	HlyD family secretion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-82)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-69)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10950.82 Da
• Isoelectric Point: 10.5783

>T105709 WP_109627206.1 NZ_CP029482:400221-400502 [Pseudomonas sp. 31-12]
MTYKLEFLPSARKEWDKLGHTLREQFKKKLAERLQLPRVPSDSLHGMPDCYKIKLRSSGYRLVYEVIDERVVVSVVAVGK
RERSAVYDRAKKR

Nucleotide

• Length: 282 bp

>T105709 NZ_CP029482:400221-400502 [Pseudomonas sp. 31-12]
ATGACCTATAAGCTCGAATTCCTGCCGTCCGCACGCAAGGAGTGGGACAAACTGGGTCATACATTGCGAGAGCAATTCAA
AAAGAAATTGGCAGAGCGACTTCAGCTCCCGCGAGTACCGTCAGACTCACTACATGGAATGCCTGACTGCTACAAAATCA
AGTTGCGCTCATCGGGGTACAGATTGGTGTACGAAGTTATTGATGAACGTGTAGTCGTTTCCGTGGTGGCAGTGGGTAAG
CGTGAACGCAGCGCTGTTTACGACCGAGCCAAGAAACGTTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8909.26 Da
• Isoelectric Point: 4.7123

>AT105709 WP_109627204.1 NZ_CP029482:399986-400231 [Pseudomonas sp. 31-12]
MQNVLADIAVSVSELKKNPSAVLNGAHGGPVAVLNHNRVMGYMVPADVFECMMERLDDLELAEIVRSRRHETPVPVNLDD
L

Nucleotide

• Length: 246 bp

>AT105709 NZ_CP029482:399986-400231 [Pseudomonas sp. 31-12]
ATGCAAAATGTTCTGGCCGACATCGCTGTCAGCGTGTCTGAGTTGAAGAAAAATCCATCAGCGGTACTGAACGGCGCTCA
TGGCGGGCCTGTGGCAGTGCTAAATCACAATCGCGTCATGGGCTACATGGTTCCGGCCGATGTTTTCGAGTGCATGATGG
AGCGACTCGATGATCTGGAACTGGCGGAAATTGTCCGCTCTCGCAGGCATGAGACACCGGTGCCGGTAAATCTGGATGAC
CTATAA