Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 548954..549094 Replicon chromosome
Accession NZ_CP029449
Organism Serratia marcescens strain CAV1761

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 548954..549050 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 548954..549094 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DKC05_RS04615 544039..544254 - 216 WP_025302459.1 helix-turn-helix transcriptional regulator -
DKC05_RS04620 544262..544825 - 564 WP_033642723.1 DUF2975 domain-containing protein -
DKC05_RS04625 544983..546182 - 1200 WP_047727768.1 trans-2-enoyl-CoA reductase family protein -
DKC05_RS04630 546469..546771 + 303 WP_047727769.1 hypothetical protein -
DKC05_RS04635 546822..547172 - 351 WP_033638116.1 DUF4377 domain-containing protein -
DKC05_RS04640 548204..548533 + 330 WP_038875697.1 DUF1493 family protein -
- 548954..549050 - 97 - - Toxin
- 548954..549094 + 141 - - Antitoxin
DKC05_RS04645 549192..549533 - 342 WP_025302452.1 YebY family protein -
DKC05_RS04650 549603..550484 - 882 WP_038875842.1 copper homeostasis membrane protein CopD -
DKC05_RS04655 550487..550903 - 417 WP_047727770.1 CopC domain-containing protein YobA -
DKC05_RS04660 551197..551700 - 504 WP_047727771.1 non-heme ferritin -
DKC05_RS04665 552041..552271 + 231 WP_033638067.1 DNA polymerase III subunit theta -
DKC05_RS04670 552336..552773 - 438 WP_038874510.1 IS200/IS605 family transposase -
DKC05_RS04675 552928..553881 - 954 WP_047730746.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 546822..562286 15464
- flank IS/Tn - - 552336..552824 488


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T105654 NZ_CP029449:c549050-548954 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT105654 NZ_CP029449:548954-549094 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References