Detailed information of TA system TA105596

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 560642..561302
• Replicon: chromosome
• Accession: NZ_CP029397
• Organism: Acinetobacter defluvii strain WCHA30

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: DJ533_RS05065
• Protein ID: WP_065994115.1
• Coordinates: 560886..561302 (+)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A2S2FAK0
• Locus tag: DJ533_RS05060
• Protein ID: WP_065994114.1
• Coordinates: 560642..560899 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DJ533_RS05040	556139..557146	+	1008	WP_065994111.1	DNA-directed RNA polymerase subunit alpha	-
DJ533_RS05045	557165..557530	+	366	WP_004281488.1	50S ribosomal protein L17	-
DJ533_RS05050	557737..559227	+	1491	WP_065994112.1	NAD(P)/FAD-dependent oxidoreductase	-
DJ533_RS05055	559289..560461	-	1173	WP_065994113.1	acyl-CoA dehydrogenase family protein	-
DJ533_RS05060	560642..560899	+	258	WP_065994114.1	succinate dehydrogenase assembly factor 2	Antitoxin
DJ533_RS05065	560886..561302	+	417	WP_065994115.1	hypothetical protein	Toxin
DJ533_RS05070	561852..562997	+	1146	WP_065994116.1	hypothetical protein	-
DJ533_RS05075	563085..563666	+	582	WP_065994117.1	rhombosortase	-
DJ533_RS05080	564017..566212	+	2196	WP_065994118.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 16488.76 Da
• Isoelectric Point: 10.1059

>T105596 WP_065994115.1 NZ_CP029397:560886-561302 [Acinetobacter defluvii]
MSMVNLEPYRCFKLKPSRYWRWFQLFLGVAIIILLYPILTLWLWLPCVLLLTVSGYMFSLKPQVAQFEQLDGQIWSLKFV
QNQKIQHVKIKQMIDHIFYIVIYVEDVSNSNKLSSFIVWQDQLAQKSWKMLKTQAKLA

Nucleotide

• Length: 417 bp

>T105596 NZ_CP029397:560886-561302 [Acinetobacter defluvii]
ATGTCCATGGTTAATCTTGAACCTTATCGCTGTTTTAAGCTGAAACCAAGCCGATATTGGCGATGGTTTCAGCTTTTTTT
GGGTGTAGCCATTATAATTCTTCTCTACCCAATCTTAACCCTATGGCTGTGGTTACCTTGTGTCTTACTTTTGACTGTTT
CAGGTTATATGTTCAGTCTAAAACCGCAAGTTGCACAGTTTGAACAATTAGATGGACAGATTTGGTCGCTTAAATTTGTG
CAAAATCAGAAGATACAACACGTAAAAATAAAGCAAATGATTGATCACATTTTTTATATTGTGATCTATGTTGAAGATGT
TTCTAATTCAAATAAACTTTCAAGTTTTATTGTTTGGCAAGATCAATTAGCACAAAAAAGCTGGAAAATGTTAAAAACAC
AGGCAAAGTTAGCTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10283.83 Da
• Isoelectric Point: 4.7341

>AT105596 WP_065994114.1 NZ_CP029397:560642-560899 [Acinetobacter defluvii]
MFEELTLEERKVIYRARRGLKEIDVYFDPYVKQHYLQADATEKALFKELVDQEDPDLLDWFMEVSEPPKPELRQLIIKLK
QYVHG

Nucleotide

• Length: 258 bp

>AT105596 NZ_CP029397:560642-560899 [Acinetobacter defluvii]
ATGTTTGAAGAATTAACTTTGGAAGAACGTAAAGTTATTTATCGTGCACGTCGTGGTTTGAAAGAAATTGATGTTTATTT
TGATCCTTATGTAAAACAACATTATTTACAGGCAGACGCAACCGAAAAAGCTTTATTTAAAGAATTGGTTGACCAAGAAG
ACCCAGATTTACTCGATTGGTTTATGGAAGTATCTGAGCCTCCAAAACCAGAATTAAGACAACTTATTATTAAACTTAAA
CAATATGTCCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A2S2FAK0