Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1497261..1497406 Replicon chromosome
Accession NZ_CP029388
Organism Klebsiella pneumoniae subsp. pneumoniae strain SCKP040074

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1497268..1497370 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1497261..1497406 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVG30_RS09385 1492794..1494227 + 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CVG30_RS09390 1494343..1494582 + 240 WP_002911393.1 YebV family protein -
CVG30_RS09395 1494680..1494871 + 192 WP_002911395.1 YebW family protein -
CVG30_RS09400 1494868..1495521 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
CVG30_RS09405 1495678..1496645 + 968 Protein_1502 DUF535 domain-containing protein -
CVG30_RS28665 1496750..1496893 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1497261..1497406 + 146 - - Antitoxin
- 1497268..1497370 - 103 - - Toxin
CVG30_RS09415 1497529..1497867 - 339 WP_002911404.1 YebY family protein -
CVG30_RS09420 1497884..1498753 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
CVG30_RS09425 1498757..1499131 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CVG30_RS09430 1499244..1499474 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CVG30_RS09435 1499553..1500212 + 660 WP_021440386.1 exodeoxyribonuclease X -
CVG30_RS09440 1500216..1502276 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T105578 NZ_CP029388:c1497370-1497268 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT105578 NZ_CP029388:1497261-1497406 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References