105390

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 566783..567144 Replicon chromosome
Accession NZ_CP029280
Organism Xanthomonas phaseoli pv. phaseoli strain Px100

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag DGM85_RS02295 Protein ID WP_005914328.1
Coordinates 567010..567144 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag DGM85_RS02290 Protein ID WP_039568455.1
Coordinates 566783..566935 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGM85_RS02260 (DGM85_02425) 561863..562546 - 684 WP_039568445.1 dTMP kinase -
DGM85_RS02265 (DGM85_02435) 563015..563557 - 543 WP_039568446.1 GTPase -
DGM85_RS02270 (DGM85_02440) 563554..564471 - 918 WP_039568451.1 hypothetical protein -
DGM85_RS02275 (DGM85_02445) 564557..564916 - 360 WP_003486613.1 hypothetical protein -
DGM85_RS02280 (DGM85_02450) 564980..565432 - 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
DGM85_RS02285 (DGM85_02455) 565753..566676 + 924 WP_041019108.1 arginase -
DGM85_RS02290 (DGM85_02460) 566783..566935 + 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
DGM85_RS02295 (DGM85_02465) 567010..567144 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
DGM85_RS02300 (DGM85_02470) 567374..567583 + 210 WP_003486601.1 CsbD family protein -
DGM85_RS02305 (DGM85_02475) 567765..569054 + 1290 WP_039568540.1 tryptophan--tRNA ligase -
DGM85_RS02310 (DGM85_02480) 569184..570128 + 945 WP_039568459.1 MBL fold metallo-hydrolase -
DGM85_RS02315 (DGM85_02485) 570196..570451 - 256 Protein_457 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T105390 WP_005914328.1 NZ_CP029280:567010-567144 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T105390 NZ_CP029280:567010-567144 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT105390 WP_039568455.1 NZ_CP029280:566783-566935 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT105390 NZ_CP029280:566783-566935 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGTCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References