105387

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 522372..522733 Replicon chromosome
Accession NZ_CP029277
Organism Xanthomonas phaseoli pv. phaseoli strain PR1

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag DGM93_RS02110 Protein ID WP_005914328.1
Coordinates 522599..522733 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag DGM93_RS02105 Protein ID WP_039568455.1
Coordinates 522372..522524 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGM93_RS02075 (DGM93_02250) 517444..518127 - 684 WP_039568445.1 dTMP kinase -
DGM93_RS02080 (DGM93_02260) 518596..519138 - 543 WP_039568446.1 GTPase -
DGM93_RS02085 (DGM93_02265) 519135..520049 - 915 WP_039587901.1 hypothetical protein -
DGM93_RS02090 (DGM93_02270) 520146..520505 - 360 WP_003486613.1 hypothetical protein -
DGM93_RS02095 (DGM93_02275) 520569..521021 - 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
DGM93_RS02100 (DGM93_02280) 521342..522265 + 924 WP_215824806.1 arginase -
DGM93_RS02105 (DGM93_02285) 522372..522524 + 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
DGM93_RS02110 (DGM93_02290) 522599..522733 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
DGM93_RS02115 (DGM93_02295) 522962..523171 + 210 WP_003486601.1 CsbD family protein -
DGM93_RS02120 (DGM93_02300) 523353..524642 + 1290 WP_039568540.1 tryptophan--tRNA ligase -
DGM93_RS02125 (DGM93_02305) 524772..525716 + 945 WP_039568459.1 MBL fold metallo-hydrolase -
DGM93_RS02130 (DGM93_02310) 525784..526039 - 256 Protein_419 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T105387 WP_005914328.1 NZ_CP029277:522599-522733 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T105387 NZ_CP029277:522599-522733 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT105387 WP_039568455.1 NZ_CP029277:522372-522524 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT105387 NZ_CP029277:522372-522524 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGTCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References