Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4609818..4610179 Replicon chromosome
Accession NZ_CP029275
Organism Xanthomonas citri strain M11

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag DGM98_RS19940 Protein ID WP_005914328.1
Coordinates 4609818..4609952 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag DGM98_RS19945 Protein ID WP_003486606.1
Coordinates 4610027..4610179 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGM98_RS19925 (DGM98_20885) 4606847..4607890 - 1044 WP_099802478.1 MBL fold metallo-hydrolase -
DGM98_RS19930 (DGM98_20890) 4607920..4609209 - 1290 WP_007966942.1 tryptophan--tRNA ligase -
DGM98_RS19935 (DGM98_20895) 4609382..4609591 - 210 WP_016904514.1 CsbD family protein -
DGM98_RS19940 (DGM98_20900) 4609818..4609952 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
DGM98_RS19945 (DGM98_20905) 4610027..4610179 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
DGM98_RS19950 (DGM98_20910) 4610286..4611209 - 924 WP_007966941.1 arginase -
DGM98_RS19955 (DGM98_20915) 4611530..4611982 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
DGM98_RS19960 (DGM98_20920) 4612046..4612405 + 360 WP_003486613.1 hypothetical protein -
DGM98_RS19965 (DGM98_20925) 4612502..4613419 + 918 WP_007966939.1 hypothetical protein -
DGM98_RS19970 (DGM98_20930) 4613416..4613958 + 543 WP_003486615.1 GTPase -
DGM98_RS19975 (DGM98_20935) 4614442..4615125 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T105384 WP_005914328.1 NZ_CP029275:c4609952-4609818 [Xanthomonas citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T105384 NZ_CP029275:c4609952-4609818 [Xanthomonas citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT105384 WP_003486606.1 NZ_CP029275:c4610179-4610027 [Xanthomonas citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT105384 NZ_CP029275:c4610179-4610027 [Xanthomonas citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGTAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References