105380

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4777821..4778182 Replicon chromosome
Accession NZ_CP029273
Organism Xanthomonas citri strain T21

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag DGN02_RS20260 Protein ID WP_005914328.1
Coordinates 4777821..4777955 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag DGN02_RS20265 Protein ID WP_003486606.1
Coordinates 4778030..4778182 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGN02_RS20245 (DGN02_21035) 4774850..4775893 - 1044 WP_099803183.1 MBL fold metallo-hydrolase -
DGN02_RS20250 (DGN02_21040) 4775923..4777212 - 1290 WP_099803184.1 tryptophan--tRNA ligase -
DGN02_RS20255 (DGN02_21045) 4777385..4777594 - 210 WP_016904514.1 CsbD family protein -
DGN02_RS20260 (DGN02_21050) 4777821..4777955 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
DGN02_RS20265 (DGN02_21055) 4778030..4778182 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
DGN02_RS20270 (DGN02_21060) 4778289..4779212 - 924 WP_007966941.1 arginase -
DGN02_RS20275 (DGN02_21065) 4779533..4779985 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
DGN02_RS20280 (DGN02_21070) 4780049..4780408 + 360 WP_003486613.1 hypothetical protein -
DGN02_RS20285 (DGN02_21075) 4780505..4781422 + 918 WP_007966939.1 hypothetical protein -
DGN02_RS20290 (DGN02_21080) 4781419..4781961 + 543 WP_099803185.1 GTPase -
DGN02_RS20295 (DGN02_21085) 4782441..4783124 + 684 WP_099803186.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T105380 WP_005914328.1 NZ_CP029273:c4777955-4777821 [Xanthomonas citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T105380 NZ_CP029273:c4777955-4777821 [Xanthomonas citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT105380 WP_003486606.1 NZ_CP029273:c4778182-4778030 [Xanthomonas citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT105380 NZ_CP029273:c4778182-4778030 [Xanthomonas citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References