105376

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4659633..4659994 Replicon chromosome
Accession NZ_CP029270
Organism Xanthomonas citri pv. fuscans strain FH61

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag DGN07_RS20145 Protein ID WP_005914328.1
Coordinates 4659633..4659767 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag DGN07_RS20150 Protein ID WP_003486606.1
Coordinates 4659842..4659994 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGN07_RS20130 (DGN07_20940) 4656662..4657705 - 1044 WP_033481136.1 MBL fold metallo-hydrolase -
DGN07_RS20135 (DGN07_20945) 4657735..4659024 - 1290 WP_022560228.1 tryptophan--tRNA ligase -
DGN07_RS20140 (DGN07_20950) 4659197..4659406 - 210 WP_016904514.1 CsbD family protein -
DGN07_RS20145 (DGN07_20955) 4659633..4659767 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
DGN07_RS20150 (DGN07_20960) 4659842..4659994 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
DGN07_RS20155 (DGN07_20965) 4660101..4661024 - 924 WP_007966941.1 arginase -
DGN07_RS20160 (DGN07_20970) 4661345..4661797 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
DGN07_RS20165 (DGN07_20975) 4661861..4662220 + 360 WP_003486613.1 hypothetical protein -
DGN07_RS20170 (DGN07_20980) 4662317..4663231 + 915 WP_022560229.1 hypothetical protein -
DGN07_RS20175 (DGN07_20985) 4663228..4663770 + 543 WP_003486615.1 GTPase -
DGN07_RS20180 (DGN07_20990) 4664250..4664933 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T105376 WP_005914328.1 NZ_CP029270:c4659767-4659633 [Xanthomonas citri pv. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T105376 NZ_CP029270:c4659767-4659633 [Xanthomonas citri pv. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT105376 WP_003486606.1 NZ_CP029270:c4659994-4659842 [Xanthomonas citri pv. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT105376 NZ_CP029270:c4659994-4659842 [Xanthomonas citri pv. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References