Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 64698..65242 Replicon chromosome
Accession NZ_CP029270
Organism Xanthomonas citri pv. fuscans strain FH61

Toxin (Protein)


Gene name relE Uniprot ID A0A808FED4
Locus tag DGN07_RS00265 Protein ID WP_022557812.1
Coordinates 64943..65242 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag DGN07_RS00260 Protein ID WP_005912560.1
Coordinates 64698..64955 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGN07_RS00245 (DGN07_00275) 59789..61300 - 1512 WP_215825264.1 ribonuclease H-like domain-containing protein -
DGN07_RS00250 (DGN07_00280) 61297..63792 - 2496 WP_022557810.1 DEAD/DEAH box helicase -
DGN07_RS00255 (DGN07_00285) 63970..64632 + 663 WP_029818121.1 hemolysin III family protein -
DGN07_RS00260 (DGN07_00290) 64698..64955 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DGN07_RS00265 (DGN07_00295) 64943..65242 + 300 WP_022557812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DGN07_RS00275 (DGN07_00305) 65422..66321 - 900 WP_022557813.1 SDR family NAD(P)-dependent oxidoreductase -
DGN07_RS00280 (DGN07_00310) 66381..67118 - 738 WP_022557814.1 SDR family oxidoreductase -
DGN07_RS00285 (DGN07_00315) 67244..68155 + 912 WP_039732218.1 LysR family transcriptional regulator -
DGN07_RS00290 (DGN07_00320) 68370..69434 - 1065 WP_033481295.1 ATP-grasp fold amidoligase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11279.07 Da        Isoelectric Point: 10.1539

>T105375 WP_022557812.1 NZ_CP029270:64943-65242 [Xanthomonas citri pv. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIERPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T105375 NZ_CP029270:64943-65242 [Xanthomonas citri pv. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACGCCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT105375 WP_005912560.1 NZ_CP029270:64698-64955 [Xanthomonas citri pv. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT105375 NZ_CP029270:64698-64955 [Xanthomonas citri pv. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808FED4

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References