Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 5007474..5008011 Replicon chromosome
Accession NZ_CP029267
Organism Xanthomonas citri pv. fuscans strain M12

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9YU06
Locus tag DGN11_RS21340 Protein ID WP_017158383.1
Coordinates 5007730..5008011 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7X9UWY6
Locus tag DGN11_RS21335 Protein ID WP_017158384.1
Coordinates 5007474..5007743 (+) Length 90 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGN11_RS21305 (DGN11_22350) 5002736..5003344 + 609 WP_017154888.1 hypothetical protein -
DGN11_RS21310 (DGN11_22355) 5003457..5004089 + 633 WP_007966093.1 ParA family protein -
DGN11_RS21315 (DGN11_22360) 5004082..5004414 + 333 WP_007966095.1 hypothetical protein -
DGN11_RS21320 (DGN11_22365) 5004481..5004765 + 285 WP_017154887.1 hypothetical protein -
DGN11_RS21325 (DGN11_22370) 5004772..5005959 + 1188 WP_022560475.1 zeta toxin family protein -
DGN11_RS21330 (DGN11_22375) 5006403..5007365 + 963 WP_022560476.1 recombinase family protein -
DGN11_RS21335 (DGN11_22380) 5007474..5007743 + 270 WP_017158384.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DGN11_RS21340 (DGN11_22385) 5007730..5008011 + 282 WP_017158383.1 type II toxin-antitoxin system YafQ family toxin Toxin
DGN11_RS21345 (DGN11_22390) 5008149..5008502 - 354 WP_033481414.1 hypothetical protein -
DGN11_RS21350 (DGN11_22395) 5008548..5009255 - 708 WP_022560478.1 StbB family protein -
DGN11_RS21355 (DGN11_22400) 5009252..5009698 - 447 WP_033481413.1 hypothetical protein -
DGN11_RS21360 (DGN11_22405) 5010044..5010439 + 396 WP_022560480.1 hypothetical protein -
DGN11_RS21365 (DGN11_22410) 5010537..5010806 + 270 WP_033481412.1 hypothetical protein -
DGN11_RS21370 (DGN11_22415) 5010803..5011096 + 294 WP_011345592.1 type II toxin-antitoxin system RelE/ParE family toxin -
DGN11_RS21375 (DGN11_22420) 5011209..5011829 + 621 WP_011345593.1 hypothetical protein -
DGN11_RS21380 (DGN11_22425) 5012028..5012369 + 342 WP_029561219.1 hypothetical protein -
DGN11_RS21385 (DGN11_22430) 5012441..5012638 + 198 WP_022560481.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5002736..5021371 18635


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-93)

Antitoxin

(7-86)


Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10679.06 Da        Isoelectric Point: 8.9188

>T105373 WP_017158383.1 NZ_CP029267:5007730-5008011 [Xanthomonas citri pv. fuscans]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Download         Length: 282 bp

>T105373 NZ_CP029267:5007730-5008011 [Xanthomonas citri pv. fuscans]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9719.10 Da        Isoelectric Point: 5.6976

>AT105373 WP_017158384.1 NZ_CP029267:5007474-5007743 [Xanthomonas citri pv. fuscans]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Download         Length: 270 bp

>AT105373 NZ_CP029267:5007474-5007743 [Xanthomonas citri pv. fuscans]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7X9YU06


Antitoxin

Source ID Structure
AlphaFold DB A0A7X9UWY6

References