Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4548376..4548737 Replicon chromosome
Accession NZ_CP029267
Organism Xanthomonas citri pv. fuscans strain M12

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag DGN11_RS19490 Protein ID WP_005914328.1
Coordinates 4548376..4548510 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag DGN11_RS19495 Protein ID WP_003486606.1
Coordinates 4548585..4548737 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGN11_RS19475 (DGN11_20405) 4545405..4546448 - 1044 WP_033481136.1 MBL fold metallo-hydrolase -
DGN11_RS19480 (DGN11_20410) 4546478..4547767 - 1290 WP_022560228.1 tryptophan--tRNA ligase -
DGN11_RS19485 (DGN11_20415) 4547940..4548149 - 210 WP_016904514.1 CsbD family protein -
DGN11_RS19490 (DGN11_20420) 4548376..4548510 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
DGN11_RS19495 (DGN11_20425) 4548585..4548737 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
DGN11_RS19500 (DGN11_20430) 4548844..4549767 - 924 WP_007966941.1 arginase -
DGN11_RS19505 (DGN11_20435) 4550088..4550540 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
DGN11_RS19510 (DGN11_20440) 4550604..4550963 + 360 WP_003486613.1 hypothetical protein -
DGN11_RS19515 (DGN11_20445) 4551060..4551974 + 915 WP_022560229.1 hypothetical protein -
DGN11_RS19520 (DGN11_20450) 4551971..4552513 + 543 WP_003486615.1 GTPase -
DGN11_RS19525 (DGN11_20455) 4552993..4553676 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T105372 WP_005914328.1 NZ_CP029267:c4548510-4548376 [Xanthomonas citri pv. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T105372 NZ_CP029267:c4548510-4548376 [Xanthomonas citri pv. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT105372 WP_003486606.1 NZ_CP029267:c4548737-4548585 [Xanthomonas citri pv. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT105372 NZ_CP029267:c4548737-4548585 [Xanthomonas citri pv. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References