105369

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4667020..4667381 Replicon chromosome
Accession NZ_CP029264
Organism Xanthomonas citri pv. fuscans strain PR8F

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag DGN16_RS20210 Protein ID WP_005914328.1
Coordinates 4667020..4667154 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag DGN16_RS20215 Protein ID WP_003486606.1
Coordinates 4667229..4667381 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGN16_RS20195 (DGN16_21015) 4664049..4665092 - 1044 WP_033481136.1 MBL fold metallo-hydrolase -
DGN16_RS20200 (DGN16_21020) 4665122..4666411 - 1290 WP_022560228.1 tryptophan--tRNA ligase -
DGN16_RS20205 (DGN16_21025) 4666584..4666793 - 210 WP_016904514.1 CsbD family protein -
DGN16_RS20210 (DGN16_21030) 4667020..4667154 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
DGN16_RS20215 (DGN16_21035) 4667229..4667381 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
DGN16_RS20220 (DGN16_21040) 4667488..4668411 - 924 WP_007966941.1 arginase -
DGN16_RS20225 (DGN16_21045) 4668732..4669184 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
DGN16_RS20230 (DGN16_21050) 4669248..4669607 + 360 WP_003486613.1 hypothetical protein -
DGN16_RS20235 (DGN16_21055) 4669704..4670618 + 915 WP_022560229.1 hypothetical protein -
DGN16_RS20240 (DGN16_21060) 4670615..4671157 + 543 WP_003486615.1 GTPase -
DGN16_RS20245 (DGN16_21065) 4671637..4672320 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T105369 WP_005914328.1 NZ_CP029264:c4667154-4667020 [Xanthomonas citri pv. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T105369 NZ_CP029264:c4667154-4667020 [Xanthomonas citri pv. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT105369 WP_003486606.1 NZ_CP029264:c4667381-4667229 [Xanthomonas citri pv. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT105369 NZ_CP029264:c4667381-4667229 [Xanthomonas citri pv. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References