Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4389885..4390250 Replicon chromosome
Accession NZ_CP029263
Organism Xanthomonas sp. MLO165

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag DGN21_RS18460 Protein ID WP_016904515.1
Coordinates 4389885..4390019 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag DGN21_RS18465 Protein ID WP_006451340.1
Coordinates 4390098..4390250 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGN21_RS18445 (DGN21_18875) 4386952..4387896 - 945 WP_215825019.1 MBL fold metallo-hydrolase -
DGN21_RS18450 (DGN21_18880) 4387955..4389244 - 1290 WP_215825020.1 tryptophan--tRNA ligase -
DGN21_RS18455 (DGN21_18885) 4389426..4389635 - 210 WP_016904514.1 CsbD family protein -
DGN21_RS18460 (DGN21_18890) 4389885..4390019 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
DGN21_RS18465 (DGN21_18895) 4390098..4390250 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
DGN21_RS18470 (DGN21_18900) 4390360..4391283 - 924 WP_046346094.1 arginase -
DGN21_RS18475 (DGN21_18905) 4391762..4392214 + 453 WP_054591235.1 roadblock/LC7 domain-containing protein -
DGN21_RS18480 (DGN21_18910) 4392279..4392638 + 360 WP_016904518.1 hypothetical protein -
DGN21_RS18485 (DGN21_18915) 4392733..4393650 + 918 WP_104575692.1 hypothetical protein -
DGN21_RS18490 (DGN21_18920) 4393647..4394189 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T105367 WP_016904515.1 NZ_CP029263:c4390019-4389885 [Xanthomonas sp. MLO165]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T105367 NZ_CP029263:c4390019-4389885 [Xanthomonas sp. MLO165]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGGTGTTGTCGGTCGGTATGCTGTCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCTGCGCGCAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT105367 WP_006451340.1 NZ_CP029263:c4390250-4390098 [Xanthomonas sp. MLO165]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT105367 NZ_CP029263:c4390250-4390098 [Xanthomonas sp. MLO165]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACTGGCTGCAACACCATGGCCGGCGC
CGGCAAGGACATGCAGGGTGCAGGCGAGAAGGTCGAAAAGAAGGCCGACAACTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References